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A Simple Methodology to Differentiate Changes in Bioavailability From Changes in Clearance Following Oral Dosing of Metabolized Drugs

Clinical Pharmacology & Therapeutics(2020)10.1002/cpt.1828Source: DataRank Database

A Simple Methodology to Differentiate Changes in Bioavailability From Changes in Clearance Following Oral Dosing of Metabolized Drugs is a research paper published in Clinical Pharmacology & Therapeutics (2020). On theSindex it has a DataRank of 0. It has been cited 9 times.

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Open Access9 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)Impact (FWCI 1.39)OA: greenTopics (67)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (2)

Leslie Z. Benet ORCID,Jasleen K. Sodhi ORCID

Live enrichment

PubMed:32150643 PMC:PMC7478330 OpenAlex:https://openalex.org/W3010480539

American Foundation for Pharmaceutical Education

Grant: R25 GM56847

National Institutes of Health

Grant: P30 DK026743

NIGMS NIH HHS

Grant: R25 GM056847

National Institutes of Health

Grant: 5R25GM056847-10

Biomedical Science Research Career Enhancement Program

National Institutes of Health

Grant: 5P30DK026743-27

UCSF Liver Core Center

FWCI

1.39

Citation Percentile

0.8%

Citation Trend

2020

2021

2022

2023

2026

greenLicense: Wiley Online Library User Agreement

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7478330

publisherhttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fcpt.1828

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.1828

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.1002/cpt.1828

Fields of Study

Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and ProtectionAnalytical Methods in Pharmaceuticals0301 basic medicine03 medical and health sciences0302 clinical medicineAdministration, IntravenousAdministration, OralBiological AvailabilityBiotransformationCytochrome P-450 CYP3ACytochrome P-450 CYP3A InducersCytochrome P-450 CYP3A InhibitorsDrug InteractionsHumansMetabolic Clearance RateMidazolamModels, BiologicalRisk Assessment

MeSH Terms

Administration, OralBiological AvailabilityBiotransformationDrug InteractionsHumansMetabolic Clearance RateMidazolamModels, BiologicalRisk AssessmentCytochrome P-450 CYP3AAdministration, IntravenousCytochrome P-450 CYP3A InhibitorsCytochrome P-450 CYP3A Inducers

Keywords

BioavailabilityDosingPharmacologyPharmacokineticsClearanceMetabolic clearance rateMedicineChemistryUrologyOralMidazolam610Administration, OralBiological AvailabilityModels, BiologicalRisk AssessmentModels617Cytochrome P-450 CYP3AHumansDrug InteractionsPharmacology & PharmacyDental/Oral and Craniofacial DiseaseBiotransformationBiomedical and Clinical SciencesEvaluation of treatments and therapeutic interventionsCytochrome P-450 CYP3A InducersPharmacology and Pharmaceutical SciencesBiological6.1 PharmaceuticalsAdministrationCytochrome P-450 CYP3A InhibitorsAdministration, IntravenousPatient SafetyIntravenous

Sustainable Development Goals

SDG 0: Reduced inequalities