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Intestinal Metabolism of Diclofenac by Polymorphic UGT2B17 Correlates with its Highly Variable Pharmacokinetics and Safety across Populations

Clinical Pharmacology & Therapeutics(2023)10.1002/cpt.2907Source: DataRank Database

Intestinal Metabolism of Diclofenac by Polymorphic UGT2B17 Correlates with its Highly Variable Pharmacokinetics and Safety across Populations is a research paper published in Clinical Pharmacology & Therapeutics (2023). On theSindex it has a DataRank of 0. It has been cited 19 times.

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0DataRank · unranked

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Open Access19 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (1 grants)Impact (FWCI 4.26)OA: hybridTopics (38)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Scott Heyward ORCID,Bhagwat Prasad ORCID,Deepak Ahire ORCID

Live enrichment

PubMed:37042794 PMC:PMC10330245 OpenAlex:https://openalex.org/W4365135502

NICHD NIH HHS

Grant: R01 HD081299

FWCI

4.26

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpt.2907

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpt.2907

publisherhttps://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2907

journalhttps://doi.org/10.1002/cpt.2907

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37042794

Fields of Study

Pharmacogenetics and Drug MetabolismInflammatory mediators and NSAID effectsDrug-Induced Hepatotoxicity and ProtectionHumansChildFemaleDiclofenacMicrosomes, LiverLiverHepatocytesHeterozygoteGlucuronosyltransferaseMinor Histocompatibility Antigens

MeSH Terms

ChildDiclofenacFemaleHeterozygoteHumansLiverMicrosomes, LiverGlucuronosyltransferaseMinor Histocompatibility AntigensHepatocytes

Keywords

DiclofenacUGT2B7PharmacokineticsPharmacologyPopulationBiologyDrug metabolismMicrosomeGlucuronosyltransferaseGlucuronidationChemistryDrugMedicineIn vitroBiochemistry

Sustainable Development Goals

SDG 0: Partnerships for the goals