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Screening Method for the Identification of Compounds That Activate Pregnane X Receptor

Current Protocols(2022)10.1002/cpz1.615Source: DataRank Database

Screening Method for the Identification of Compounds That Activate Pregnane X Receptor is a research paper published in Current Protocols (2022). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 0.34)OA: greenTopics (35)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Srilatha Sakamuru ORCID,Menghang Xia ORCID,Caitlin Lynch ORCID

Live enrichment

PubMed:36469580 PMC:PMC9904169 OpenAlex:https://openalex.org/W4310726138

Intramural NIH HHS

Grant: Z99 TR999999

Intramural NIH HHS

Grant: ZIA TR000038

FWCI

0.34

Citation Percentile

0.6%

Citation Trend

2023

2024

2026

greenLicense: http://creativecommons.org/licenses/by-nc/4.0/

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9904169

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/cpz1.615

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.1002/cpz1.615

publisherhttps://currentprotocols.onlinelibrary.wiley.com/doi/pdf/10.1002/cpz1.615

Fields of Study

Pharmacogenetics and Drug MetabolismHormonal Regulation and HypertensionAdenosine and Purinergic SignalingHumansPregnane X ReceptorCytochrome P-450 CYP3AReceptors, SteroidReceptors, Cytoplasmic and NuclearLuciferases

MeSH Terms

Pregnane X ReceptorHumansLuciferasesReceptors, SteroidReceptors, Cytoplasmic and NuclearCytochrome P-450 CYP3A

Keywords

Pregnane X receptorLuciferaseNuclear receptorCYP3A4Reporter geneComputational biologyBiologyTransfectionHigh-throughput screeningCell biologyPharmacologyChemistryCytochrome P450BiochemistryGene expressionGeneEnzymeTranscription factorQuantitative High-throughput ScreeningPxr Reporter Gene Assay