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Therapeutic efficacy of FASN inhibition in preclinical models of HCC

Hepatology(2022)10.1002/hep.32359Source: DataRank Database

Therapeutic efficacy of FASN inhibition in preclinical models of HCC is a research paper published in Hepatology (2022). On theSindex it has a DataRank of 0. It has been cited 126 times.

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Open Access126 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (15 grants)OA: greenTopics (108)Linked Datasets (25)DataCite Reuse (25)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Authors (14)

Yi Zhou ORCID,Hongwei Xu ORCID,Xue Wang ORCID,Yi Zhang ORCID,Runze Shang ORCID

Live enrichment

PubMed:35076948 PMC:PMC9309180

National Institutes of Health

Grant: P30DK026743

National Natural Science Foundation of China

Grant: 82002967

Deutsche Krebshilfe

Grant: 70113922

NCI NIH HHS

Grant: U01 CA288375

NCI NIH HHS

Grant: R01 CA250227

NCI NIH HHS

Grant: R01 CA239251

National Institutes of Health

Grant: R03CA288375

NCI NIH HHS

Grant: R01 CA204586

NCI NIH HHS

Grant: R01 CA221916

NCI NIH HHS

Grant: R03 CA249236

National Institutes of Health

Grant: 5R01CA239251-02

Signaling pathways during hepatocarcinogenesis

National Institutes of Health

Grant: 1U01CA288375-01

Therapeutic modulation of a proteomic HCC risk signature with statins in patients with liver cirrhosis

National Institutes of Health

Grant: 5R01CA204586-05

Yap and beta-catenin interactions in liver: Implications in Pathophysiology

National Institutes of Health

Grant: 5P30DK026743-27

UCSF Liver Core Center

National Institutes of Health

Grant: 5R01CA250227-04

Investigating multifactorial beta-catenin activation in hepatocellular cancers

greenLicense: Wiley Online Library User Agreement

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9309180

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/hep.32359

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.1002/hep.32359

publisherhttps://journals.lww.com/10.1002/hep.32359

https://doi.org/10.1002/hep.32359

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

LiverCell Line, TumorAnimalsMammalsHumansMiceCarcinoma, HepatocellularLiver NeoplasmsFatty LiverAnilidesPyridinesPhosphoric Monoester HydrolasesAntineoplastic AgentsProtein Kinase InhibitorsCell ProliferationProto-Oncogene Proteins c-metProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesFatty Acid SynthasesFatty Acid Synthase, Type ITensinsSorafenib

Keywords

PyridinesType ITensins (mesh)Medical Biochemistry and MetabolomicsMiceTensins1103 Clinical Sciences (for)Hepatocellular (mesh)Animals (mesh)AnilidesCell Proliferation (mesh)32 Biomedical and Clinical Sciences (for-2020)Liver Disease (rcdc)Sorafenib (mesh)CancerCancer (rcdc)MammalsHumans (mesh)Tumor3 Good Health and Well Being (sdg)Pyridines (mesh)Liver DiseaseTOR Serine-Threonine KinasesLiver NeoplasmsMice (mesh)Protein Kinase Inhibitors (mesh)TOR Serine-Threonine Kinases (mesh)Proto-Oncogene Proteins c-metSorafenibAnilides (mesh)Fatty Acid Synthase, Type IAntineoplastic Agents (mesh)Liver5.1 PharmaceuticalsFatty Acid SynthaseTumor (mesh)Digestive Diseases (rcdc)Liver CancerFatty Liver (mesh)Phosphoric Monoester Hydrolases (mesh)Liver (mesh)Carcinoma, HepatocellularProto-Oncogene Proteins c-met (mesh)Clinical SciencesOncology and CarcinogenesisImmunology6101107 Immunology (for)Antineoplastic AgentsMammals (mesh)Cell LineRare Diseases (rcdc)Rare Diseases5.1 Pharmaceuticals (hrcs-rac)615Cell Line, TumorGeneticsAnimalsHumans3204 Immunology (for-2020)Protein Kinase Inhibitors3202 Clinical Sciences (for-2020)Cell ProliferationBiomedical and Clinical SciencesGastroenterology & HepatologyGenetics (rcdc)CarcinomaHepatocellular1101 Medical Biochemistry and Metabolomics (for)Cancer (hrcs-hc)Phosphoric Monoester HydrolasesLiver Neoplasms (mesh)Type I (mesh)Fatty LiverGood Health and Well Being3211 Oncology and Carcinogenesis (for-2020)Liver Cancer (rcdc)Fatty Acid Synthases (mesh)Gastroenterology & Hepatology (science-metrix)Fatty Acid SynthasesDigestive DiseasesProto-Oncogene Proteins c-aktProto-Oncogene Proteins c-akt (mesh)

Sustainable Development Goals

SDG 3: 3. Good health

Additional file 1 of Exploring the dynamic three-dimensional chromatin architecture and transcriptional landscape in goose liver tissues underlying metabolic adaptations induced by a high-fat diet

10.6084/m9.figshare.26699027.v1figshare

Additional file 1 of Exploring the dynamic three-dimensional chromatin architecture and transcriptional landscape in goose liver tissues underlying metabolic adaptations induced by a high-fat diet

10.6084/m9.figshare.26699027figshare

Additional file 2 of Exploring the dynamic three-dimensional chromatin architecture and transcriptional landscape in goose liver tissues underlying metabolic adaptations induced by a high-fat diet

10.6084/m9.figshare.26699030.v1figshare

Additional file 2 of Exploring the dynamic three-dimensional chromatin architecture and transcriptional landscape in goose liver tissues underlying metabolic adaptations induced by a high-fat diet

10.6084/m9.figshare.26699030figshare

Additional file 3 of Exploring the dynamic three-dimensional chromatin architecture and transcriptional landscape in goose liver tissues underlying metabolic adaptations induced by a high-fat diet

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Additional file 3 of Exploring the dynamic three-dimensional chromatin architecture and transcriptional landscape in goose liver tissues underlying metabolic adaptations induced by a high-fat diet

10.6084/m9.figshare.26699033figshare

Additional file 4 of Exploring the dynamic three-dimensional chromatin architecture and transcriptional landscape in goose liver tissues underlying metabolic adaptations induced by a high-fat diet

10.6084/m9.figshare.26699036.v1figshare

Additional file 4 of Exploring the dynamic three-dimensional chromatin architecture and transcriptional landscape in goose liver tissues underlying metabolic adaptations induced by a high-fat diet

10.6084/m9.figshare.26699036figshare

Additional file 5 of Exploring the dynamic three-dimensional chromatin architecture and transcriptional landscape in goose liver tissues underlying metabolic adaptations induced by a high-fat diet

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Additional file 5 of Exploring the dynamic three-dimensional chromatin architecture and transcriptional landscape in goose liver tissues underlying metabolic adaptations induced by a high-fat diet

10.6084/m9.figshare.26699039figshare

Additional file 6 of Exploring the dynamic three-dimensional chromatin architecture and transcriptional landscape in goose liver tissues underlying metabolic adaptations induced by a high-fat diet

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Additional file 6 of Exploring the dynamic three-dimensional chromatin architecture and transcriptional landscape in goose liver tissues underlying metabolic adaptations induced by a high-fat diet

10.6084/m9.figshare.26699042figshare

Additional file 4 of Comparative analysis of gene expression between mice and humans in acetaminophen-induced liver injury by integrating bioinformatics analysis

10.6084/m9.figshare.26699201.v1figshare

Additional file 4 of Comparative analysis of gene expression between mice and humans in acetaminophen-induced liver injury by integrating bioinformatics analysis

10.6084/m9.figshare.26699201figshare

Additional file 3 of Comparative analysis of gene expression between mice and humans in acetaminophen-induced liver injury by integrating bioinformatics analysis

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Additional file 3 of Comparative analysis of gene expression between mice and humans in acetaminophen-induced liver injury by integrating bioinformatics analysis

10.6084/m9.figshare.26699198.v1figshare

Additional file 2 of Comparative analysis of gene expression between mice and humans in acetaminophen-induced liver injury by integrating bioinformatics analysis

10.6084/m9.figshare.25506748figshare

Additional file 2 of Comparative analysis of gene expression between mice and humans in acetaminophen-induced liver injury by integrating bioinformatics analysis

10.6084/m9.figshare.25506748.v1figshare

Additional file 1 of Comparative analysis of gene expression between mice and humans in acetaminophen-induced liver injury by integrating bioinformatics analysis

10.6084/m9.figshare.25506608.v1figshare

Additional file 1 of Comparative analysis of gene expression between mice and humans in acetaminophen-induced liver injury by integrating bioinformatics analysis

10.6084/m9.figshare.25506608figshare