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Transcriptome profiling reveals that VNPP433‐3β, the lead next‐generation galeterone analog inhibits prostate cancer stem cells by downregulating epithelial–mesenchymal transition and stem cell markers

Molecular Carcinogenesis(2022)10.1002/mc.23406Source: DataRank Database

Transcriptome profiling reveals that VNPP433‐3β, the lead next‐generation galeterone analog inhibits prostate cancer stem cells by downregulating epithelial–mesenchymal transition and stem cell markers is a research paper published in Molecular Carcinogenesis (2022). On theSindex it has a DataRank of 0. It has been cited 31 times.

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Open Access31 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 4.22)OA: hybridTopics (42)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Retheesh S. Thankan,Puranik Purushottamachar,Weiliang Huang ORCID,Maureen A. Kane ORCID,Yuji Zhang ORCID

Live enrichment

PubMed:35512605 PMC:PMC9322274 OpenAlex:https://openalex.org/W4229011327

NCI NIH HHS

Grant: R01 CA224696

National Institutes of Health

FWCI

4.22

Citation Percentile

1.0%

Citation Trend

2022

2023

2024

2025

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1002/mc.23406

publisherhttps://doi.org/10.1002/mc.23406

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/mc.23406

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.1002/mc.23406

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35512605

Fields of Study

Prostate Cancer Treatment and ResearchFOXO transcription factor regulationCancer Cells and Metastasis

MeSH Terms

AndrostadienesBenzimidazolesHumansMaleProstateReceptors, AndrogenNeoplastic Stem CellsGene Expression ProfilingCell Line, TumorEpithelial-Mesenchymal TransitionProstatic Neoplasms, Castration-Resistant

Keywords

Prostate cancerCancer stem cellBiologyEpithelial–mesenchymal transitionTranscriptomeCancer researchMetastasisStem cellAndrogen receptorKLF4CD44CarcinogenesisLNCaPCancerTranscription factorSOX2CellCell biologyGeneGene expressionGeneticsCastration Resistant Prostate CancerRna SequencingMnk-eif4eAr/ar-v7 DegraderVnpp433-3βLead Next Generation Galeterone AnalogProstate Cancer Transcriptome

Sustainable Development Goals

SDG 0: Good health and well-being