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FGF21 and GDF15 Act Synergistically to Regulate Systemic Metabolic Homeostasis in Mice Lacking OPA1 in Thermogenic Adipocytes

Obesity(2025)10.1002/oby.70004Source: DataRank Database

FGF21 and GDF15 Act Synergistically to Regulate Systemic Metabolic Homeostasis in Mice Lacking OPA1 in Thermogenic Adipocytes is a research paper published in Obesity (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (10 grants)Impact (FWCI 0.74)OA: hybridTopics (57)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Jayashree Jena ORCID,Ayushi Sood ORCID,Shelly Roitershtein,David Smith ORCID,Renata O. Pereira

Live enrichment

PubMed:40897647 PMC:PMC12477105 OpenAlex:https://openalex.org/W4413936164

American Heart Association

Grant: 15SDG25710438

American Heart Association

Grant: 25POST1377539

American Heart Association

Grant: 25PRE1361334

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: NIH DK125405

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: T32DK112751‐01

NIDDK NIH HHS

Grant: T32 DK112751

NIDDK NIH HHS

Grant: R01 DK125405

NIDDK NIH HHS

Grant: T32DK112751-01

National Institutes of Health

Grant: 5R01DK125405-02

The role of the integrated stress response in brown adipose tissue-mediated metabolic adaptations

National Institutes of Health

Grant: 5T32DK112751-03

Diabetes Research Training Program

FWCI

0.74

Citation Percentile

0.7%

Citation Trend

2026

hybridLicense: cc-by

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/oby.70004

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/oby.70004

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/oby.70004

journalhttps://doi.org/10.1002/oby.70004

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40897647

Fields of Study

Adipose Tissue and MetabolismFibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsAdipose Tissue, BrownEnergy MetabolismFibroblast Growth FactorsGlucoseHomeostasisInsulin ResistanceMaleMice, Inbred C57BLObesityAdipocytesMice, KnockoutGTP PhosphohydrolasesThermogenesisMiceGrowth Differentiation Factor 15Diet, High-Fat

Keywords

FGF21Insulin resistanceGDF15Energy homeostasisEndocrinologyInternal medicineAdipose tissueGlucose homeostasisThermogenesismitochondrial fusionHomeostasisBiologyInsulinMedicineFibroblast growth factorObesityBiochemistryReceptorMitochondrial DNABrown adipose tissueMitochondrial StressMice, KnockoutMaleGrowth Differentiation Factor 15Diet, High-FatGTP PhosphohydrolasesFibroblast Growth FactorsMice, Inbred C57BLMiceGlucoseAdipose Tissue, BrownAdipocytesAnimalsEnergy MetabolismORIGINAL ARTICLE