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Human‐induced pluripotent stem cell‐derived cardiomyocytes: Cardiovascular properties and metabolism and pharmacokinetics of deuterated mexiletine analogs

Pharmacology Research & Perspectives(2021)10.1002/prp2.828Source: DataRank Database

Human‐induced pluripotent stem cell‐derived cardiomyocytes: Cardiovascular properties and metabolism and pharmacokinetics of deuterated mexiletine analogs is a research paper published in Pharmacology Research & Perspectives (2021). On theSindex it has a DataRank of 0. It has been cited 6 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access6 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 0.48)OA: goldTopics (39)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Karl J. Okolotowicz,Mark Johnson ORCID,Wesley L. McKeithan ORCID,Mark Mercola ORCID,John R. Cashman ORCID

Live enrichment

PubMed:34327875 PMC:PMC8322572 OpenAlex:https://openalex.org/W3183972724

California Institute for Regenerative Medicine

Grant: TR4‐06857

National Institutes of Health

Grant: P30CA030199

FWCI

0.48

Citation Percentile

0.6%

Citation Trend

2021

2022

2024

goldLicense: cc-by-nc-nd

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/prp2.828

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/prp2.828

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.828

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.1002/prp2.828

publisherhttps://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.828

Fields of Study

Chemical Reactions and IsotopesCardiac electrophysiology and arrhythmiasIon channel regulation and function

MeSH Terms

AnimalsBehavior, AnimalCells, CulturedFemaleHumansLiverLong QT SyndromeMaleMexiletineMice, Inbred BALB CSeizuresRats, Sprague-DawleyMyocytes, CardiacMiceRatsInduced Pluripotent Stem Cells

Keywords

MexiletinePharmacologyInduced pluripotent stem cellhERGChemistryPharmacokineticsToxicityDrugSodium channelPotassium channelMedicineBiochemistrySodiumInternal medicineMetabolismArrhythmiasQt ProlongationDeuterated Phenyl MexiletinesHuman-induced Pluripotent Stem Cells-derived CardiomyocytesPhenyl Mexiletine

Sustainable Development Goals

SDG 0: Good health and well-being