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Great Wall: A Generalized Dose Optimization Design for Drug Combination Trials Maximizing Survival Benefit

Pharmaceutical Statistics(2025)10.1002/pst.70049Source: DataRank Database

Great Wall: A Generalized Dose Optimization Design for Drug Combination Trials Maximizing Survival Benefit is a research paper published in Pharmaceutical Statistics (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)Impact (FWCI 0.00)OA: hybridTopics (36)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Yingjie Qiu ORCID,Yi Zhao ORCID,Isabella Wan,Lang Li ORCID,Suyu Liu ORCID

Live enrichment

PubMed:41221813 PMC:PMC12606548 OpenAlex:https://openalex.org/W4416257149

National Cancer Institute

Grant: R21 CA264257

National Cancer Institute

Grant: P30 CA082709

National Cancer Institute

Grant: P30CA142543

National Cancer Institute

Grant: U01CA248240

National Institute of General Medical Sciences

Grant: R01 GM150808

Indiana CTSI

Indiana Clinical and Translational Sciences Institute

Ralph W. and Grace M. Showalter Research Trust Fund

Indiana CTSI

Ralph W. and Grace M. Showalter Research Trust Fund

FWCI

0.00

Citation Percentile

0.3%

hybridLicense: cc-by

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pst.70049

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pst.70049

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/pst.70049

journalhttps://doi.org/10.1002/pst.70049

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41221813

Fields of Study

Statistical Methods in Clinical TrialsOptimal Experimental Design MethodsAdvanced Causal Inference TechniquesHumansResearch DesignDose-Response Relationship, DrugAlgorithmsComputer SimulationClinical Trials, Phase I as TopicClinical Trials, Phase II as TopicDrug CombinationsRandomized Controlled Trials as TopicDrug Therapy, Combination

MeSH Terms

AlgorithmsComputer SimulationDose-Response Relationship, DrugDrug CombinationsDrug Therapy, CombinationHumansResearch DesignRandomized Controlled Trials as TopicClinical Trials, Phase I as TopicClinical Trials, Phase II as Topic

Keywords

Clinical trialModular designClinical study designMaximum tolerated doseSet (abstract data type)RandomizationOptimal designImmunotherapySurvival OutcomePhase I–ii Clinical TrialDrug‐combination TrialDose RandomizationDose Optimization Design