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Nanoscale Organization of TRAIL Trimers using DNA Origami to Promote Clustering of Death Receptor and Cancer Cell Apoptosis

Small(2023)10.1002/smll.202206160Source: DataRank Database

Nanoscale Organization of TRAIL Trimers using DNA Origami to Promote Clustering of Death Receptor and Cancer Cell Apoptosis is a research paper published in Small (2023). On theSindex it has a DataRank of 0.984. It has been cited 27 times, with 26 citing works in its 1-hop citation network.

N/A

0.984DataRank · unranked

Scored on demand from live citation data

27 citations · 26 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 2.51)OA: closedTopics (47)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 51%Citation Network 49%

Base Score Contribution

0.500

From this paper's citation signal

Citation Network Contribution

0.484

From 19 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 26 citers.

A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns
Nature Nanotechnology202471 citations49 referencesContributes 0.087
Inducing Cancer Cell Killing Using DNA Nanostructure-Mediated Superclustering of Death Receptors
Nano Letters20254 citations38 referencesContributes 0.042
Chiroplasmonic DNA Scaffolded “Fusilli” Structures
Nano Letters20244 citations41 referencesContributes 0.039
Snoopligase-catalyzed molecular glue enables efficient generation of hyperoligomerized TRAIL variant with enhanced antitumor effect
Journal of Controlled Release20234 citations43 referencesContributes 0.037
Self-Illuminating Nanoagonist Simultaneously Induces Dual Cell Death Pathways via Death Receptor Clustering for Cancer Therapy
ACS Nano20245 citations48 referencesContributes 0.037

Authors (16)

Keman Cheng,Qingqing Feng,Guangna Liu,Jie Liang ORCID,Xiaotu Ma ORCID

Live enrichment

PubMed:36890776 OpenAlex:https://openalex.org/W4323653437

Natural Science Foundation of Beijing Municipality

Grant: Z200020

Natural Science Foundation of Beijing Municipality

Grant: X.Z

Beijing Nova Program

Grant: Z201100006820031

Beijing Nova Program

Grant: X.Z.

National Natural Science Foundation of China

Grant: 32222045

National Natural Science Foundation of China

Grant: 32171384

FWCI

2.51

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

closedLicense: http://onlinelibrary.wiley.com/termsAndConditions#vor

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1002/smll.202206160

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.1002/smll.202206160

journalhttps://doi.org/10.1002/smll.202206160

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36890776

Fields of Study

Advanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryBiochemical and Structural CharacterizationLigandsReceptors, TNF-Related Apoptosis-Inducing LigandTNF-Related Apoptosis-Inducing LigandApoptosisTumor Necrosis Factor-alphaCell Line, TumorNeoplasms

MeSH Terms

LigandsNeoplasmsTumor Necrosis Factor-alphaApoptosisCell Line, TumorReceptors, TNF-Related Apoptosis-Inducing LigandTNF-Related Apoptosis-Inducing Ligand

Keywords

TrimerDNA origamiDNAApoptosisChemistryReceptorLigand (biochemistry)MonomerProgrammed cell deathDNA damageCluster analysisBiophysicsCancer cellCytotoxicityNanotechnologyCell biologyDimerCancerBiochemistryIn vitroBiologyMaterials scienceGeneticsComputer sciencePolymertumor therapyDeath ReceptorsNanoscale OrganizationTrail TrimersInterligand Distance

Sustainable Development Goals

SDG 0: Good health and well-being