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Biochemical Assays to Directly Assess Smoothened Activation by a Conformationally Sensitive Nanobody

Methods in molecular biology(2021)10.1007/978-1-0716-1701-4_13Source: DataRank Database

Biochemical Assays to Directly Assess Smoothened Activation by a Conformationally Sensitive Nanobody is a research paper published in Methods in molecular biology (2021). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 0.00)OA: greenTopics (39)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (2)

Aashish Manglik ORCID,Ishan Deshpande ORCID

Live enrichment

PubMed:34562250 PMC:PMC9618365 OpenAlex:https://openalex.org/W3201516544

NIGMS NIH HHS

Grant: R01 GM138992

NIH HHS

Grant: DP5 OD023048

Swiss National Science Foundation

Grant: 180798

Regulation of Hedgehog signaling by the Smoothened receptor

National Institutes of Health

Grant: 5DP5OD023048-05

Molecular Mechanisms of Iron Homeostasis

FWCI

0.00

Citation Percentile

0.2%

greenLicense: Springer TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9618365

publisherhttps://link.springer.com/content/pdf/10.1007/978-1-0716-1701-4_13

book serieshttps://doi.org/10.1007/978-1-0716-1701-4_13

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34562250

Fields of Study

Hedgehog Signaling Pathway StudiesGenomics and Chromatin DynamicsChromatin Remodeling and Cancer0301 basic medicine0303 health sciences03 medical and health sciencesHedgehog ProteinsMembrane ProteinsReceptors, G-Protein-CoupledSignal TransductionSmoothened ReceptorSterols

MeSH Terms

Smoothened ReceptorMembrane ProteinsSterolsSignal TransductionReceptors, G-Protein-CoupledHedgehog Proteins

Keywords

SmoothenedHedgehog signaling pathwayHedgehogCell biologyPatchedTransmembrane proteinBiologyChemistryBiochemistrySignal transductionReceptorNanobodyHedgehog SignalingFluorescence Size-exclusion ChromatographyNbsmo8Smoothened ActivationSterolsMembrane ProteinsHedgehog ProteinsSmoothened ReceptorReceptors, G-Protein-Coupled

Sustainable Development Goals

SDG 0: Good health and well-being