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Increased plasma concentrations of 6-oxo-methylphenidate in CES1 G134E carriers following a single oral dose of methylphenidate

Medicinal Chemistry Research(2025)10.1007/s00044-025-03477-3Source: DataRank Database

Increased plasma concentrations of 6-oxo-methylphenidate in CES1 G134E carriers following a single oral dose of methylphenidate is a research paper published in Medicinal Chemistry Research (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (1 grants)Impact (FWCI 0.00)OA: greenTopics (15)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

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Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Philip W. Melchert,Ahmed Awad ORCID,Christopher R. McCurdy ORCID,Beth Krone ORCID,Jeffrey Newcorn

Live enrichment

PubMed:41567292 PMC:PMC12818952 OpenAlex:https://openalex.org/W4414764700

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Grant: R01 HD093612

FWCI

0.00

Citation Percentile

0.3%

greenLicense: https://www.springernature.com/gp/researchers/text-and-data-mining

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12818952/

publisherhttps://link.springer.com/content/pdf/10.1007/s00044-025-03477-3.pdf

publisherhttps://link.springer.com/article/10.1007/s00044-025-03477-3/fulltext.html

journalhttps://doi.org/10.1007/s00044-025-03477-3

Fields of Study

Pharmacogenetics and Drug MetabolismEnzyme Catalysis and ImmobilizationParkinson's Disease Mechanisms and Treatments

Keywords

MethylphenidatePharmacokineticsPlasma concentrationActive metaboliteMetabolismMetaboliteOral administrationGlycineOxidative stressADHD6-Oxo-methylphenidateCes1 G143e

Increased plasma concentrations of 6-oxo-methylphenidate in CES1 G134E carriers following a single oral dose of methylphenidate

FAIR Checklist

Authors (11)

Funding (1 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)