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Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h

Diabetologia(2024)10.1007/s00125-024-06214-4Source: DataRank Database

Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h is a research paper published in Diabetologia (2024). On theSindex it has a DataRank of 0.378. It has been cited 11 times, with 11 citing works in its 1-hop citation network.

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0.378DataRank · unranked

Scored on demand from live citation data

Open Access11 citations · 11 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (17 grants)Impact (FWCI 4.67)OA: hybridTopics (51)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 99%Citation Network 1%

Base Score Contribution

0.373

From this paper's citation signal

Citation Network Contribution

5.37 × 10⁻³

From 1 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 11 citers.

β-cell heterogeneity and molecular plasticity in type 2 diabetes: multi-omics perspectives and the role of gut microbiota
Frontiers in Cell and Developmental Biology20262 citations174 referencesContributes 0.006
Physiologically Relevant Simulation of Carbohydrate Digestion: From Glycemic Index Estimation to Intestinal Cellular Responses
Foods20250 citations41 referencesContributes 0.000
Integrated meta-analysis of public human pancreatic single-cell transcriptomes reveals distinct beta-cell state trajectories across aging and diabetes
bioRxiv (Cold Spring Harbor Laboratory)20260 citations39 referencesContributes 0.000
Gene-Environment Interaction through single-cell transcriptomics in Type 2 diabetes
Research Square20260 citations25 referencesContributes 0.000
AI-Powered Multi-Omics Analysis for Novel Diabetes Biomarker Discovery: Interlinking Metabolomic, Genomic, and Proteomic Networks
Biosciences Biotechnology Research Asia20260 citations93 referencesContributes 0.000

Authors (16)

Henry J. Taylor ORCID,Lori L. Bonnycastle ORCID,Dongxiang Xue ORCID,Brian N. Lee ORCID,Zoe Weiss ORCID

Live enrichment

PubMed:38967666 PMC:PMC11447040 OpenAlex:https://openalex.org/W4400370662

American Diabetes Association

Grant: 9-22-PDFPM-06

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: 1U01DK127777-01

Determining the Intrinsic and Environmental Signal Contributing to Early T1D Progression

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: R01 DK116075-01A1

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: R01 DK119667-01A1

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: R01 DK124463

National Institutes of Health

Grant: ZIA-HG000024

National Institute for Health Research (NIHR)

Grant: NIHR203312

British Heart Foundation

Grant: RG/18/13/33946

British Heart Foundation

Grant: RG/F/23/110103

Intramural NIH HHS

Grant: ZIA HG000024

British Heart Foundation

Grant: RE/18/1/34212

British Heart Foundation

Grant: CH/12/2/29428

National Institutes of Health

Grant: 1R01DK119667-01A1

Metallothionein 1E as a Central Regulator of Human Pancreatic Beta Cell Function and Survival

National Institutes of Health

Grant: 1ZIAHG000024-26

Genetic analysis of type II diabetes in Finnish population

National Institutes of Health

Grant: 5R01DK116075-03

A High Throughput Screening to Identify Compounds Rescuing Human Pancreatic Beta Cell Function in Diabetic Conditions

National Institutes of Health

Grant: 1R01DK124463-01

A High Content Chemical Screen to Identify the Drug Candidates Promoting Human Beta Cell Proliferation

Gates Cambridge Trust

FWCI

4.67

Citation Percentile

1.0%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://link.springer.com/content/pdf/10.1007/s00125-024-06214-4.pdf

publisherhttps://link.springer.com/content/pdf/10.1007/s00125-024-06214-4.pdf

publisherhttps://link.springer.com/article/10.1007/s00125-024-06214-4/fulltext.html

journalhttps://doi.org/10.1007/s00125-024-06214-4

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38967666

Fields of Study

Pancreatic function and diabetesSingle-cell and spatial transcriptomicsDiabetes and associated disorders0303 health sciences03 medical and health sciences

MeSH Terms

Diabetes Mellitus, Type 2GlucoseHumansHyperglycemiaInsulinIslets of LangerhansGene Expression ProfilingInsulin-Secreting CellsSingle-Cell AnalysisTranscriptome

Keywords

IsletGlucose homeostasisBeta cellTranscriptomeEndocrinologyPancreatic isletsInternal medicineDiabetes mellitusGene expression profilingBiologyPancreasType 2 diabetesGeneCellGene expressionAlpha cellHomeostasisIn vitroMedicineInsulin resistanceGeneticsGenomicsIsletsTranscriptomicsSingle-cellGsisArticleIslets of LangerhansGlucoseDiabetes Mellitus, Type 2Insulin-Secreting CellsHyperglycemiaFOS: Biological sciencesHumansInsulinSingle-Cell Analysis

Sustainable Development Goals

SDG 0: Good health and well-being

Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (16)

Funding (17 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)