Identification of transcriptomic sepsis endotypes in sub-Saharan Africa: derivation, validation, and global alignment in two Ugandan cohorts is a dataset published in Intensive Care Medicine (2025). On theSindex it has a DataRank of 0.294, placing it in the top 55.6% of the data-sharing corpus. It has been cited 5 times, with 4 citing works in its 1-hop citation network. Its calibrated FAIR score is 56/100.
Ranks in the top 56% for downstream scientific impact
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“Proteomic data from RESERVE‑U‑2‑TOR and RESERVE‑U‑1‑EBB are available in Dryad at https:// doi. org/ 10. 5061/ dryad. b2rbn zsq2.”
The paper provides a DOI for the proteomic data, which is a persistent identifier scheme. [majority verdict 'yes' (3/5 passes agreed)]
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“NIH/NCBI Sequence Read Archive”
The paper names established repositories (SRA via dbGaP, and Dryad) as the holders of the data. [majority verdict 'yes' (4/5 passes agreed)]
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“RNAseq data from the RESERVE‑U‑2‑TOR cohort are available in the NIH/NCBI Sequence Read Archive through dbGaP under accession number phs003914.v1.p1.”— not found in the paper; verdict downgraded
The dataset identifiers appear only in the body text (Data availability section) and not as reference-list entries. [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (3/5 passes agreed)]
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“RNAseq data from the RESERVE‑U‑2‑TOR cohort are available in the NIH/NCBI Sequence Read Archive through dbGaP under accession number phs003914.v1.p1.”— not found in the paper; verdict downgraded
The data availability statement points to repository records with specific accessions and DOIs, corresponding to Colavizza category 3 (link to archived data in a public repository). [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“We analyzed data from two prospective observational cohorts of critically ill adults with sepsis in Uganda (discovery cohort [Tororo, rural], N = 243; validation cohort [Entebbe, urban], N = 112).”
The paper describes the dataset content (cohorts, sample sizes) in running prose without an itemized inventory or dedicated section. [majority verdict 'partial' (4/5 passes agreed)]
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“In concordance with participant consent and institutional certification of genomic data sharing, RNAseq data from RESERVE‑U‑2‑TOR will be available to investigators with an IRB‑approved protocol.”
The paper states a specified, followable access process (IRB protocol and Data Access Committee request) for the controlled-access cohort, which is a precondition. [majority verdict 'partial' (2/5 passes agreed)]
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“RNAseq data from the RESERVE‑U‑2‑TOR cohort are available in the NIH/NCBI Sequence Read Archive through dbGaP under accession number phs003914. v1.p1. In concordance with participant consent and institutional certification of genomic data sharing, RNAseq data from RESERVE‑U‑2‑TOR will be available to investigators with an IRB‑approved protocol.”
The paper describes the access process but does not apply an explicit access-level label from the standard vocabulary. [majority verdict 'partial' (4/5 passes agreed)]
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
“RNAseq data from the RESERVE‑U‑2‑TOR cohort are available in the NIH/NCBI Sequence Read Archive through dbGaP under accession number phs003914.v1.p1.”— not found in the paper; verdict downgraded
The paper names the NIH/NIAID Data Access Committee as the institutional gatekeeper for the controlled-access RNAseq data from the RESERVE-U-2-TOR cohort. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
The paper does not state any persistence commitment or availability timing for the data beyond the fact that they are available now.
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
The paper does not name any file format for the released data (RNAseq or proteomic).
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
“Gene set enrichment analysis (GSEA; Gene Ontology resource [c5.all.v2024.1.Hs.symbols.gmt])”— not found in the paper; verdict downgraded
The Gene Ontology is a community standard vocabulary applied to the data analysis. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (2/5 passes agreed)]
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
“GRCh38”— not found in the paper; verdict downgraded
The paper gives the identifier of an external resource: the human reference genome assembly GRCh38. [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (3/5 passes agreed)]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
The paper does not attach any reuse license or terms to the data; the CC-BY-NC license applies only to the article.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
“phs003914.v1.p1”— not found in the paper; verdict downgraded
The dbGaP accession includes a version suffix (v1.p1), pinning the snapshot. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
“Analytic R code is available in Github at https:// github. com/ mjc22 44/ Uganda‑ Sepsis‑ Endot ype‑ Deriv ation‑ and‑ Valid ation.”
The paper provides a machine-resolvable GitHub repository URL for the analytic code. [majority verdict 'yes' (4/5 passes agreed)]
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“K23AI163364”
The paper lists specific grant numbers (e.g., K23AI163364) from the National Institute of Allergy and Infectious Diseases. [majority verdict 'yes' (4/5 passes agreed)]
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“Illumina NovaSeq X Plus”
The paper names specific instruments and software used to produce the data (e.g., Illumina NovaSeq X Plus, STAR, featureCounts).
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
No documentation object (README, codebook) is named as accompanying the data. [majority verdict 'no' (3/5 passes agreed)]
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.269
From this paper's citation signal
Citation Network Contribution
0.0248
From 3 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 4 citers.
National Center for Advancing Translational Sciences
Grant: UL1TR001873
Fogarty International Center
Grant: D43TW009607
National Institute of Allergy and Infectious Diseases
Grant: K23AI163364
National Institute of Allergy and Infectious Diseases
Grant: R01AI184997
National Institutes of Health
Grant: 5K23AI163364-02
Subtyping sepsis in Uganda using clinical, pathogen, and host response profiling
National Institutes of Health
Grant: 3UL1TR001873-07S1
Clinical and Translational Science Award
National Institutes of Health
Grant: 3D43TW009607-04S1
International Research Training on TB and Other Pulmonary Complications of HIV
National Institutes of Health
Grant: 5R01AI184997-02
Multidimensional and longitudinal immune profiling of sepsis in Uganda
Burroughs Wellcome Fund
Division of Intramural Research, National Institute of Allergy and Infectious Diseases
FWCI
3.70
Citation Percentile
0.9%
Citation Trend
Fields of Study
MeSH Terms
Keywords