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Inhibition of head and neck squamous cell carcinoma by Bruton’s tyrosine kinase inhibitor ibrutinib is associated with reduction of immunosuppressive T cells

Cancer Immunology Immunotherapy(2025)10.1007/s00262-025-04081-5Source: DataRank Database

Inhibition of head and neck squamous cell carcinoma by Bruton’s tyrosine kinase inhibitor ibrutinib is associated with reduction of immunosuppressive T cells is a research paper published in Cancer Immunology Immunotherapy (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access3 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)Impact (FWCI 2.22)OA: goldTopics (64)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Felipe F. Lamenza ORCID,Puja Upadhaya,Nathan Ryan ORCID,Natalie Kazmierowicz,Pete Jordanides

Live enrichment

PubMed:40445239 PMC:PMC12125455 OpenAlex:https://openalex.org/W4410895133

National Institutes of Health

Grant: DP1DA054344

American Cancer Society

Grant: RSG-19079-01-TBG

NIDCR NIH HHS

Grant: R01 DE033906

National Institutes of Health

Grant: 1DP1DA054344-01

X chromosome inactivation in sex disparities to substance use disorder

National Institutes of Health

Grant: 5R01DE033906-02

The oral glucocorticoid system in oral carcinogenesis and its modulation for improved treatment outcomes

FWCI

2.22

Citation Percentile

0.9%

Citation Trend

2025

2026

goldLicense: cc-by-nc-nd

journalhttps://link.springer.com/content/pdf/10.1007/s00262-025-04081-5.pdf

publisherhttps://link.springer.com/content/pdf/10.1007/s00262-025-04081-5.pdf

publisherhttps://link.springer.com/article/10.1007/s00262-025-04081-5/fulltext.html

journalhttps://doi.org/10.1007/s00262-025-04081-5

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40445239

Fields of Study

Chronic Lymphocytic Leukemia ResearchLymphoma Diagnosis and TreatmentCAR-T cell therapy research03 medical and health sciences0302 clinical medicine

MeSH Terms

Squamous Cell Carcinoma of Head and NeckAgammaglobulinaemia Tyrosine KinaseTyrosine Kinase InhibitorsAdenineAnimalsCarcinoma, Squamous CellHead and Neck NeoplasmsHumansPiperidinesPyrazolesPyrimidinesT-LymphocytesLymphocytes, Tumor-InfiltratingXenograft Model Antitumor AssaysCell Line, TumorProtein Kinase InhibitorsMiceTumor Microenvironment

Keywords

IbrutinibBruton's tyrosine kinaseHead and neck squamous-cell carcinomaMedicineTyrosine-kinase inhibitorHead and neckTyrosine kinaseCancer researchBasal cellInternal medicineOncologyHead and neck cancerLeukemiaCancerReceptorChronic lymphocytic leukemiaSurgeryT cellsInterleukin 10HnsccT-LymphocytesTyrosine Kinase InhibitorsMiceLymphocytes, Tumor-InfiltratingPiperidinesCell Line, TumorAgammaglobulinaemia Tyrosine KinaseTumor MicroenvironmentAnimalsHumansProtein Kinase InhibitorsRC254-282Squamous Cell Carcinoma of Head and NeckResearchAdenineNeoplasms. Tumors. Oncology. Including cancer and carcinogensXenograft Model Antitumor AssaysPyrimidinesHead and Neck NeoplasmsCarcinoma, Squamous CellPyrazoles