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Biological sex and DNA repair deficiency drive Alzheimer’s disease via systemic metabolic remodeling and brain mitochondrial dysfunction

Acta Neuropathologica(2020)10.1007/s00401-020-02152-8Source: DataRank Database

Biological sex and DNA repair deficiency drive Alzheimer’s disease via systemic metabolic remodeling and brain mitochondrial dysfunction is a research paper published in Acta Neuropathologica (2020). On theSindex it has a DataRank of 0. It has been cited 76 times.

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Open Access76 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 3.86)OA: greenTopics (26)Linked Datasets (10)DataCite Reuse (10)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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Authors (11)

Vijay R. Varma ORCID,Darlene Estrada,Mansi Babbar ORCID,Sambuddha Basu ORCID,Uma V. Mahajan ORCID

Live enrichment

PubMed:32333098 OpenAlex:https://openalex.org/W3018409450

National Institute on Aging

Grant: ZIA AG00073817

National Institute on Aging

Grant: Intramural Program

FWCI

3.86

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

greenLicense: https://www.springer.com/tdm

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7537767

publisherhttps://link.springer.com/content/pdf/10.1007/s00401-020-02152-8.pdf

publisherhttps://link.springer.com/article/10.1007/s00401-020-02152-8/fulltext.html

journalhttps://doi.org/10.1007/s00401-020-02152-8

Fields of Study

Mitochondrial Function and PathologyTryptophan and brain disordersBiochemical Acid Research Studies

MeSH Terms

Alzheimer DiseaseAnimalsBrainEnergy MetabolismFemaleGlucoseHumansMaleMitochondriaSex CharacteristicsCaenorhabditis elegansDNA Repair-Deficiency DisordersLipid MetabolismMice

Keywords

Mitochondrial DNADiseaseMedicineMitochondrionBiologyNeurosciencePathologyGeneticsGene

Sustainable Development Goals

SDG 0: Good health and well-being

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10.6084/m9.figshare.19359801.v1figshare

Additional file 1 of Integrative analysis of metabolomics and proteomics reveals amino acid metabolism disorder in sepsis

10.6084/m9.figshare.19359801figshare

Additional file 2 of Integrative analysis of metabolomics and proteomics reveals amino acid metabolism disorder in sepsis

10.6084/m9.figshare.19359804.v1figshare

Additional file 2 of Integrative analysis of metabolomics and proteomics reveals amino acid metabolism disorder in sepsis

10.6084/m9.figshare.19359804figshare

Additional file 1 of Targeting vulnerable microcircuits in the ventral hippocampus of male transgenic mice to rescue Alzheimer-like social memory loss

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Additional file 1 of Targeting vulnerable microcircuits in the ventral hippocampus of male transgenic mice to rescue Alzheimer-like social memory loss

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Additional file 4 of Integrative analysis of metabolomics and proteomics reveals amino acid metabolism disorder in sepsis

10.6084/m9.figshare.19359810.v1figshare

Additional file 3 of Integrative analysis of metabolomics and proteomics reveals amino acid metabolism disorder in sepsis

10.6084/m9.figshare.19359807figshare

Additional file 4 of Integrative analysis of metabolomics and proteomics reveals amino acid metabolism disorder in sepsis

10.6084/m9.figshare.19359810figshare

Additional file 3 of Integrative analysis of metabolomics and proteomics reveals amino acid metabolism disorder in sepsis

10.6084/m9.figshare.19359807.v1figshare