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Spatial protein profiling reveals active roles for astrocytes in the chronic active lesion core during multiple sclerosis

Acta Neuropathologica(2025)10.1007/s00401-025-02953-9Source: DataRank Database

Spatial protein profiling reveals active roles for astrocytes in the chronic active lesion core during multiple sclerosis is a research paper published in Acta Neuropathologica (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 2.08)OA: hybridTopics (28)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Anthony Chomyk ORCID,Maria L. Habean,Benjamin C. Shaw ORCID,Rachel A. Tinkey,Bruce D. Trapp ORCID

Live enrichment

PubMed:41175293 PMC:PMC12579715 OpenAlex:https://openalex.org/W4415759127

National Institute of Neurological Disorders and Stroke

Grant: T32NS077888

National Institute of Neurological Disorders and Stroke

Grant: K00NS120365

National Institute of Neurological Disorders and Stroke

Grant: R35NS09730

National Institute of Neurological Disorders and Stroke

Grant: R01NS119178

National Multiple Sclerosis Society

Grant: RFA-2203-39319

National Multiple Sclerosis Society

Grant: RFA-2203-39228

NINDS NIH HHS

Grant: R35 NS097303

NCATS NIH HHS

Grant: T32 TR004520

FWCI

2.08

Citation Percentile

0.9%

Citation Trend

2026

hybridLicense: cc-by

journalhttps://link.springer.com/content/pdf/10.1007/s00401-025-02953-9.pdf

publisherhttps://link.springer.com/content/pdf/10.1007/s00401-025-02953-9.pdf

publisherhttps://link.springer.com/article/10.1007/s00401-025-02953-9/fulltext.html

journalhttps://doi.org/10.1007/s00401-025-02953-9

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41175293

Fields of Study

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration MechanismsImmunotherapy and Immune ResponsesAstrocytesHumansMultiple SclerosisFemaleMaleWhite MatterMiddle AgedAgedAdult

MeSH Terms

AdultAgedAstrocytesFemaleHumansMaleMiddle AgedMultiple SclerosisWhite Matter

Keywords

Multiple sclerosisLesionWhite matterAstrocyteMicrogliaImmune systemDownregulation and upregulation