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Highly mutated monoclonal antibody 3F2 targets a conformational and strain-restricted epitope in human immunodeficiency virus gp41 with significant antibody-dependent cell cytotoxicity

Archives of Virology(2022)10.1007/s00705-022-05518-3Source: DataRank Database

Highly mutated monoclonal antibody 3F2 targets a conformational and strain-restricted epitope in human immunodeficiency virus gp41 with significant antibody-dependent cell cytotoxicity is a research paper published in Archives of Virology (2022). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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Enrichment:Funding (3 grants)Impact (FWCI 0.15)OA: bronzeTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Sarah Baron ORCID,Jonathon Hoffman,Meghan Garrett ORCID,Hakimuddin T. Sojar,Mark D. Hicar ORCID

Live enrichment

PubMed:35871426 PMC:PMC9308897 OpenAlex:https://openalex.org/W4286809484

NIAID NIH HHS

Grant: R01 AI125119

National Institute of Allergy and Infectious Diseases

Grant: R01 AI 125119-01

National Institutes of Health

Grant: 1R01AI125119-01

The role of non-broadly neutralizing antibodies targeting gp41 structural epitopes in long term nonprogression of HIV infection

FWCI

0.15

Citation Percentile

0.4%

Citation Trend

2023

2025

bronzeLicense: Springer Nature TDM

journalhttps://link.springer.com/content/pdf/10.1007/s00705-022-05518-3.pdf

publisherhttps://link.springer.com/content/pdf/10.1007/s00705-022-05518-3.pdf

journalhttps://doi.org/10.1007/s00705-022-05518-3

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35871426

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9308897

Fields of Study

HIV Research and TreatmentImmune Cell Function and Interactionvaccines and immunoinformatics approaches0301 basic medicine0303 health sciences03 medical and health sciencesAntibodies, MonoclonalAntibody-Dependent Cell CytotoxicityEpitopesHIV AntibodiesHIV Envelope Protein gp41HIV InfectionsHIV-1HumansImmunodominant EpitopesPeptide Library

MeSH Terms

Antibodies, MonoclonalAntibody-Dependent Cell CytotoxicityEpitopesHumansHIV AntibodiesHIV-1HIV InfectionsHIV Envelope Protein gp41Immunodominant EpitopesPeptide Library

Keywords

EpitopeGp41Conformational epitopeBiologyMonoclonal antibodyVirologyAntibodyLinear epitopeEpitope mappingMolecular biologyGeneticsImmunodominant EpitopesAntibody-Dependent Cell CytotoxicityAntibodies, MonoclonalHIV InfectionsHIV AntibodiesHIV Envelope Protein gp41EpitopesPeptide LibraryHIV-1HumansOriginal Article

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Highly mutated monoclonal antibody 3F2 targets a conformational and strain-restricted epitope in human immunodeficiency virus gp41 with significant antibody-dependent cell cytotoxicity

FAIR Checklist

Authors (6)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)