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Targeting HIF1-alpha/miR-326/ITGA5 axis potentiates chemotherapy response in triple-negative breast cancer

Breast Cancer Research and Treatment(2022)10.1007/s10549-022-06569-5Source: DataRank Database

Targeting HIF1-alpha/miR-326/ITGA5 axis potentiates chemotherapy response in triple-negative breast cancer is a research paper published in Breast Cancer Research and Treatment (2022). On theSindex it has a DataRank of 0.619. It has been cited 61 times.

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0.619DataRank · unranked

Scored on demand from live citation data

Open Access61 citations

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Linked data & code

geo bioproject doi

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (12 grants)Impact (FWCI 4.55)OA: bronzeTopics (43)Linked Datasets (8)DataCite Reuse (8)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.619

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (10)

Ünal Metin Tokat ORCID,Ibrahim Oğuzhan Tarman,Özge Saatci ORCID,Pelin G. Ersan ORCID,Umar Raza ORCID

Live enrichment

PubMed:35338412 PMC:PMC9389626 OpenAlex:https://openalex.org/W4220773470

Marie Curie

Grant: PCIG14-GA-2013-631149

American Cancer Society

Grant: IRG-17-179-04

Susan G. Komen

Grant: GTDR17500160

National Cancer Institute

Grant: R01-CA267101

National Institute of General Medical Sciences

Grant: 2P20GM109091-06

Center for Targeted Therapeutics

NCI NIH HHS

Grant: R01 CA267101

NIGMS NIH HHS

Grant: P20 GM109091

European Commission

Grant: 631149

Enhancing chemotherapy response in triple negative breast cancer (TNBC) by modulating miRNA-target network and identifying biomarkers of response

National Institutes of Health

Grant: 5R01CA267101-05

Overcoming chemoresistance in triple negative breast cancer

Higher Education Commision, Pakistan

Türkiye Bilimsel ve Teknolojik Araştirma Kurumu

Fonds de Recherche du Québec - Santé

FWCI

4.55

Citation Percentile

1.0%

Citation Trend

2022

2023

2024

2025

2026

bronzeLicense: Springer TDM

journalhttps://link.springer.com/content/pdf/10.1007/s10549-022-06569-5.pdf

publisherhttps://link.springer.com/content/pdf/10.1007/s10549-022-06569-5.pdf

publisherhttps://link.springer.com/article/10.1007/s10549-022-06569-5/fulltext.html

journalhttps://doi.org/10.1007/s10549-022-06569-5

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35338412

Fields of Study

Cancer, Hypoxia, and MetabolismCell Adhesion Molecules ResearchBarrier Structure and Function Studies03 medical and health sciences0302 clinical medicine

MeSH Terms

HypoxiaHumansSignal TransductionGene Expression Regulation, NeoplasticIntegrinsMicroRNAsCell Line, TumorCell ProliferationHypoxia-Inducible Factor 1, alpha SubunitTriple Negative Breast Neoplasms

Keywords

Triple-negative breast cancerBreast cancerChemotherapyMedicineOncologyCancerAlpha (finance)Internal medicineCancer researchSurgeryHypoxiaFibronectinIntegrinChemoresistanceEcm StiffnessTnbcMir-326Mirna-mrna NetworkIntegrins610Triple Negative Breast NeoplasmsHypoxia-Inducible Factor 1, alpha SubunitGene Expression Regulation, NeoplasticMicroRNAsCell Line, TumorHumansCell ProliferationSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Additional file 1 of ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner

10.6084/m9.figshare.25223418.v1figshare

Additional file 1 of ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner

10.6084/m9.figshare.25223418figshare

Additional file 2 of ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner

10.6084/m9.figshare.25223889.v1figshare

Additional file 2 of ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner

10.6084/m9.figshare.25223889figshare

Additional file 3 of ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner

10.6084/m9.figshare.26680780.v1figshare

Additional file 3 of ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner

10.6084/m9.figshare.26680780figshare

Additional file 4 of ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner

10.6084/m9.figshare.26680783.v1figshare

Additional file 4 of ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner

10.6084/m9.figshare.26680783figshare

Targeting HIF1-alpha/miR-326/ITGA5 axis potentiates chemotherapy response in triple-negative breast cancer

FAIR Checklist

DataRank Breakdown

Authors (10)

Funding (12 grants)

Impact

Open Access

Topics

Linked Datasets (8)

Annotations (Europe PMC)