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Challenging the Relevance of Unbound Tissue-to-Blood Partition Coefficient (Kpuu) on Prediction of Drug-Drug Interactions

Pharmaceutical Research(2020)10.1007/s11095-020-02797-wSource: DataRank Database

Challenging the Relevance of Unbound Tissue-to-Blood Partition Coefficient (Kpuu) on Prediction of Drug-Drug Interactions is a research paper published in Pharmaceutical Research (2020). On theSindex it has a DataRank of 0. It has been cited 10 times.

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Scored on demand from live citation data

Open Access10 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 0.46)OA: greenTopics (70)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Shuaibing Liu ORCID,Leslie Z. Benet ORCID,Jasleen K. Sodhi ORCID

Live enrichment

PubMed:32215750 PMC:PMC7518636 OpenAlex:https://openalex.org/W3014044749

National Institute of General Medical Sciences

Grant: GM56847

American Foundation for Pharmaceutical Education

Grant: Predoctoral Fellowship

National Institutes of Health

Grant: dk026743

NIDDK NIH HHS

Grant: P30 DK026743

NIGMS NIH HHS

Grant: R25 GM056847

National Institutes of Health

Grant: 5R25GM056847-10

Biomedical Science Research Career Enhancement Program

National Institutes of Health

Grant: 5P30DK026743-27

UCSF Liver Core Center

FWCI

0.46

Citation Percentile

0.6%

Citation Trend

2021

2023

2024

2025

greenLicense: Springer TDM

repositoryhttps://escholarship.org/uc/item/0fr285t2

GREENhttps://escholarship.org/uc/item/0fr285t2

repositoryhttps://escholarship.org/uc/item/0fr285t2

publisherhttp://link.springer.com/content/pdf/10.1007/s11095-020-02797-w.pdf

publisherhttp://link.springer.com/article/10.1007/s11095-020-02797-w/fulltext.html

Fields of Study

Drug Transport and Resistance MechanismsPharmacogenetics and Drug MetabolismPharmacological Effects and Toxicity StudiesMedicineChemistry0301 basic medicine03 medical and health sciences0302 clinical medicineBloodDrug InteractionsHumansKetoconazoleLiverMidazolamModels, Chemical

MeSH Terms

BloodDrug InteractionsHumansKetoconazoleLiverMidazolamModels, Chemical

Keywords

KetoconazoleDrugDispositionPharmacologyPartition coefficientDrug-drug interactionChemistryDrug interactionPharmacokineticsMidazolamDrug metabolismEffluxMedicinePsychologyChromatographyBiochemistrydrug-drug interactionsWell-stirred ModelKpuuLiver-to-blood PartitioningLiver (mesh)ChemicalBlood (mesh)Pharmacology & Pharmacy (science-metrix)Drug Interactions (mesh)ModelsHumansDrug InteractionsPharmacology & Pharmacy32 Biomedical and Clinical Sciences (for-2020)Liver Disease (rcdc)Ketoconazole (mesh)Chemical (mesh)3214 Pharmacology and Pharmaceutical Sciences (for-2020)Humans (mesh)Midazolam (mesh)Patient Safety (rcdc)1115 Pharmacology and Pharmaceutical Sciences (for)Biomedical and Clinical SciencesLiver DiseasePharmacology and Pharmaceutical SciencesBloodLiverModels, ChemicalPatient SafetyDigestive DiseasesDigestive Diseases (rcdc)Kp(uu)

Sustainable Development Goals

SDG 0: Good health and well-being