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Synthesis and Biological Evaluation of Novel Triazine Analogs as Rad6 Inhibitors

Pharmaceutical Research(2025)10.1007/s11095-025-03838-ySource: DataRank Database

Synthesis and Biological Evaluation of Novel Triazine Analogs as Rad6 Inhibitors is a research paper published in Pharmaceutical Research (2025). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 0.00)OA: closedTopics (47)IDs (PubMed, OpenAlex)

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Authors (7)

Ambikai Gajan,Ignatius Nguyen,Shiv K. Sharma ORCID,Pratima Nangia‐Makker ORCID,Steven M. Firestine ORCID

Live enrichment

PubMed:40021546 OpenAlex:https://openalex.org/W4408047203

NIH

Grant: R21CA288314

NIH

Grant: P30 CA022453

National Institutes of Health

Grant: 3P30CA022453-37S2

Cancer Center Support Grant

National Institutes of Health

Grant: 1R21CA288314-01

Elucidation of a novel transcriptional reprogramming-induced mechanism of endocrine resistance and therapeutic targeting

FWCI

0.00

Citation Percentile

0.0%

closedLicense: Springer Nature TDM

publisherhttps://link.springer.com/content/pdf/10.1007/s11095-025-03838-y.pdf

publisherhttps://link.springer.com/article/10.1007/s11095-025-03838-y/fulltext.html

journalhttps://doi.org/10.1007/s11095-025-03838-y

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40021546

Fields of Study

Synthesis and Characterization of Heterocyclic CompoundsRetinoids in leukemia and cellular processesCancer-related Molecular Pathways01 natural sciences0104 chemical sciences

MeSH Terms

AnimalsAntineoplastic AgentsAutophagyCell MovementCell SurvivalFemaleHistonesHumansMitochondriaStructure-Activity RelationshipTriazinesUbiquitin-Conjugating EnzymesCell Line, TumorCell ProliferationMiceUbiquitination

Keywords

TriazineChemistryPharmacologyComputational biologyBiochemistryBiologyOrganic chemistryMelanomaAutophagyTriple Negative Breast CancerSmall Molecule InhibitorsUbiquitin ConjugationTriazinesCell SurvivalUbiquitinationAntineoplastic AgentsHistonesMiceStructure-Activity RelationshipCell MovementCell Line, TumorUbiquitin-Conjugating EnzymesHumansAnimalsFemaleCell Proliferation

Synthesis and Biological Evaluation of Novel Triazine Analogs as Rad6 Inhibitors

FAIR Checklist

Authors (7)

Funding (4 grants)

Impact

Open Access

Topics