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Mechanism of pH-sensitive Amphiphilic Endosomal Escape of Ionizable Lipid Nanoparticles for Cytosolic Nucleic Acid Delivery

Pharmaceutical Research(2025)10.1007/s11095-025-03890-8Source: DataRank Database

Mechanism of pH-sensitive Amphiphilic Endosomal Escape of Ionizable Lipid Nanoparticles for Cytosolic Nucleic Acid Delivery is a research paper published in Pharmaceutical Research (2025). On theSindex it has a DataRank of 0. It has been cited 32 times.

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Open Access32 citations

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Enrichment:Funding (4 grants)Impact (FWCI 14.19)OA: hybridTopics (54)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (2)

Da Sun ORCID,Zheng‐Rong Lu ORCID

Live enrichment

PubMed:40629129 PMC:PMC12304063 OpenAlex:https://openalex.org/W4412156742

National Cancer Institute

Grant: R01CA235152

National Cancer Institute

Grant: R01CA297621

National Institutes of Health

Grant: 1R01CA297621-01

Anticancer ELNP nanovaccines for curative treatmentof pancreatic cancer

National Institutes of Health

Grant: 5R01CA235152-07

Smart nanoparticles regulating oncogenic IncRNA for breast cancer therapy

FWCI

14.19

Citation Percentile

1.0%

Citation Trend

2025

2026

hybridLicense: cc-by

journalhttps://link.springer.com/content/pdf/10.1007/s11095-025-03890-8.pdf

publisherhttps://link.springer.com/content/pdf/10.1007/s11095-025-03890-8.pdf

publisherhttps://link.springer.com/article/10.1007/s11095-025-03890-8/fulltext.html

journalhttps://doi.org/10.1007/s11095-025-03890-8

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40629129

Fields of Study

RNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesLipid Membrane Structure and Behavior02 engineering and technology0210 nano-technologyHydrogen-Ion ConcentrationEndosomesHumansNanoparticlesNucleic AcidsLipidsCytosolAnimalsLipid BilayersDrug Delivery Systems

MeSH Terms

AnimalsCytosolHumansHydrogen-Ion ConcentrationLipid BilayersLipidsNucleic AcidsEndosomesDrug Delivery SystemsNanoparticles

Keywords

EndosomeAmphiphileNucleic acidChemistryBiophysicsLipid bilayerCytosolVesicleDrug deliveryBiochemistryMembraneCellOrganic chemistryBiologyNucleic Acid DeliveryLnpEndosomal EscapeIonizable LipidsPh-sensitive Cell Membrane DisruptionDrug Delivery SystemsNucleic AcidsLipid BilayersHumansNanoparticlesAnimalsReview ArticleEndosomesHydrogen-Ion ConcentrationLipids