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Blockade of A2AR improved brain perfusion and cognitive function in a mouse model of Alzheimer’s disease

GeroScience(2025)10.1007/s11357-025-01526-8Source: DataRank Database

Blockade of A2AR improved brain perfusion and cognitive function in a mouse model of Alzheimer’s disease is a research paper published in GeroScience (2025). On theSindex it has a DataRank of 0. It has been cited 6 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access6 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (9 grants)Impact (FWCI 2.44)OA: greenTopics (53)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Julia Zaccarelli‐Magalhães ORCID,Garrett A. Clemons ORCID,Cristiane T. Citadin ORCID,Julia Langman,Drew James Smith

Live enrichment

PubMed:39843732 PMC:PMC12181614 OpenAlex:https://openalex.org/W4406731968

NIH

Grant: 1R01AG081258-01A1

Protein Arginine Methyltransferases in Alzheimer's disease

NIH

Grant: 1RF1NS132291-01

Protein arginine methyltransferase-mediated vascular dementia in sickle cell disease

NIH

Grant: 1R01AG081874-01

Using Photobiomodulation to Alleviate Brain Hypoperfusion in Alzheimer's Disease

American Heart Association

Grant: 22TPA970253

American Heart Association

Grant: 23POST1018945

American Heart Association

Grant: 23CDA1051814

NINDS NIH HHS

Grant: RF1 NS132291

NIA NIH HHS

Grant: R01 AG081258

NIA NIH HHS

Grant: R01 AG081874

FWCI

2.44

Citation Percentile

0.9%

Citation Trend

2025

2026

greenLicense: Springer Nature TDM

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12181614/pdf/11357_2025_Article_1526.pdf

publisherhttps://link.springer.com/content/pdf/10.1007/s11357-025-01526-8.pdf

publisherhttps://link.springer.com/article/10.1007/s11357-025-01526-8/fulltext.html

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12181614

Fields of Study

Receptor Mechanisms and SignalingNeuroinflammation and Neurodegeneration MechanismsAdenosine and Purinergic Signaling03 medical and health sciences0302 clinical medicine

MeSH Terms

Alzheimer DiseaseAnimalsBlood-Brain BarrierBrainCerebrovascular CirculationCognitionDisease Models, AnimalFemaleMaleMice, Inbred C57BLMice, TransgenicProtein-Arginine N-MethyltransferasesPurinesReceptor, Adenosine A2AMiceAdenosine A2 Receptor Antagonists

Keywords

DiseaseNeuroscienceBlockadeCognitionPerfusionMedicineFunction (biology)Perfusion scanningCardiologyInternal medicinePsychologyBiologyReceptorAlzheimer's diseaseBrain PerfusionProtein Arginine Methyltransferase 4Adenosine A2 ReceptorMaleProtein-Arginine N-MethyltransferasesReceptor, Adenosine A2ABrainMice, TransgenicAdenosine A2 Receptor AntagonistsMice, Inbred C57BLDisease Models, AnimalMiceAlzheimer DiseaseBlood-Brain BarrierPurinesCerebrovascular CirculationAnimalsFemale