Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Aged regulatory T cells fail to control autoimmune lacrimal gland pathogenic CD4+ T cells

GeroScience(2025)10.1007/s11357-025-01576-ySource: DataRank Database

Aged regulatory T cells fail to control autoimmune lacrimal gland pathogenic CD4+ T cells is a research paper published in GeroScience (2025). On theSindex it has a DataRank of 0.315. It has been cited 4 times, with 3 citing works in its 1-hop citation network.

N/A

0.315DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access4 citations · 3 citing works in its network

Download PDF

Cite:

Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE269883

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (26 grants)Impact (FWCI 1.51)OA: greenTopics (42)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

DataRank Breakdown

Base Score 77%Citation Network 23%

Base Score Contribution

0.241

From this paper's citation signal

Citation Network Contribution

0.0736

From 1 citing papers with measurable signal

Learn more about DataRank methodology →

Top 3 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 3 citers.

Exploring mucosal cytopathology through the lens of the microbiome in Sjögren’s syndrome
CytoJournal20251 citations8 referencesContributes 0.087
Research Progress on the Regulatory Role of Treg Cells in Inflammatory Eye Diseases
Current Issues in Molecular Biology20260 citations78 referencesContributes 0.000
Age-related dry eye disease: Redefining a distinct subtype driven by aging
The Ocular Surface20260 citations191 referencesContributes 0.000

Authors (6)

Lawrence Schaefer ORCID,Gowthaman Govindarajan ORCID,Zhiyuan Yu ORCID,Jeremías G. Galletti ORCID,Cintia S. de Paiva ORCID

Live enrichment

PubMed:40053297 PMC:PMC12181515 OpenAlex:https://openalex.org/W4408228257

National Eye Institute

Grant: R01EY030447

National Eye Institute

Grant: EY-002520

National Eye Institute

Grant: EY021725

National Eye Institute

Grant: EY007001

National Eye Institute

Grant: R01EY035333

National Cancer Institute

Grant: P30CA125123

CPRIT

Grant: CPRIT-RP180672

National Institutes of Health

Grant: CA125123

National Institutes of Health

Grant: RR024574

Wellcome Trust

Grant: 221859/Z/20/Z

Agencia Nacional de Promoción Científica y Tecnológica

Grant: PICT 2020-00138

Agencia Nacional de Promoción Científica y Tecnológica

Grant: PICT 2021-00109

NEI NIH HHS

Grant: F32 EY007001

NEI NIH HHS

Grant: T32 EY007001

NCRR NIH HHS

Grant: S10 RR024574

NEI NIH HHS

Grant: P30 EY002520

NEI NIH HHS

Grant: P30 EY021725

National Institutes of Health

Grant: 5P30EY002520-40

P30 - Core Grant for Vision Research

National Institutes of Health

Grant: 2T32EY007001-26

RESEARCH TRAINING IN VISUAL SCIENCES

National Institutes of Health

Grant: 3P30CA125123-09S3

Baylor College of Medicine Cancer Center

National Institutes of Health

Grant: 1S10RR024574-01A1

BD Biosciences Special Order LSRII

National Institutes of Health

Grant: 2P30EY021725-06

P30-Center Core Grant for Vision Research

National Institutes of Health

Grant: 5R01EY030447-03

Defining the interplay of interferon-gamma and cathepsin S in age-related dry eye

Wellcome Trust

Grant: 221859

Neuroimmune pathophysiological mechanisms of ocular surface disease

National Institutes of Health

Grant: 5R01EY035333-02

Investigating the anti-inflammatory mechanisms of calorie restriction in the aged lacrimal gland

Wellcome Trust

FWCI

1.51

Citation Percentile

0.8%

Citation Trend

2025

2026

greenLicense: Springer Nature TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12181515

publisherhttps://link.springer.com/content/pdf/10.1007/s11357-025-01576-y.pdf

publisherhttps://link.springer.com/article/10.1007/s11357-025-01576-y/fulltext.html

journalhttps://doi.org/10.1007/s11357-025-01576-y

Fields of Study

T-cell and B-cell ImmunologyImmunotherapy and Immune ResponsesOcular Surface and Contact Lens03 medical and health sciences0302 clinical medicine

MeSH Terms

AnimalsDisease Models, AnimalFemaleLacrimal ApparatusMice, Inbred C57BLSjogren's SyndromeCD4-Positive T-LymphocytesMice, KnockoutT-Lymphocytes, RegulatoryMiceInterleukin-2 Receptor alpha Subunit

Keywords

Lacrimal glandImmunologyAutoimmune diseaseExocrine glandMedicineBiologyPathologyInternal medicineAntibodySecretionAgingAutoimmunityRegulatory T cellsSjögren DiseaseMhc Ii PresentationMice, KnockoutCD4-Positive T-LymphocytesMice, Inbred C57BLMiceDisease Models, AnimalSjogren's SyndromeLacrimal ApparatusInterleukin-2 Receptor alpha SubunitAnimalsFemaleT-Lymphocytes, Regulatory