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Endothelial IGF- 1R deficiency disrupts microvascular homeostasis, impairing skeletal muscle perfusion and endurance: implications for age-related sarcopenia

GeroScience(2025)10.1007/s11357-025-01653-2Source: DataRank Database

Endothelial IGF- 1R deficiency disrupts microvascular homeostasis, impairing skeletal muscle perfusion and endurance: implications for age-related sarcopenia is a research paper published in GeroScience (2025). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Enrichment:Funding (10 grants)OA: hybridTopics (17)IDs (PubMed)

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Authors (20)

Santny Shanmugarama ORCID,Roland Patai ORCID,Rafał Gulej ORCID,Janet Faakye,Dorina Nagy ORCID

Live enrichment

PubMed:23304386

National Institutes of Health

Grant: 5K01AG073614-02

Midlife Obesity, Neurovascular Senescence and Cognitive Decline

National Institutes of Health

Grant: 1RF1AG072295-01

Cerebromicrovascular rejuvenation by heterochronic blood exchange

National Institutes of Health

Grant: 5K01AG073613-05

Targeting adipose tissue thermogenesis for age-related vascular cognitive impairment

National Institutes of Health

Grant: 5R01AG068295-03

Age-related vascular cognitive impairment: role of endothelial senescence

National Institutes of Health

Grant: 5R01AG055395-07

Cerebral microhemorrhages and gait abnormalities in aging

National Institutes of Health

Grant: 1R01AG070915-01A1

The role of IGF-1 signaling in vascular smooth muscle cells in age-related vascular cognitive impairment and dementia

National Institutes of Health

Grant: 5R01NS100782-03

Radiation-induced astrocyte dysfunction and cognitive decline

National Institutes of Health

Grant: 1R01CA255840-01

Chemotherapy-induced vascular cognitive impairment: role of endothelial senescence

National Institutes of Health

Grant: 1R03AG070479-01A1

Time-restricted feeding (TRF) for prevention of age-related vascular cognitive impairment and dementia

National Institutes of Health

Grant: 5R21AG080775-02

Time restricted eating for prevention of age-related vascular cognitive decline in older adults

hybridLicense: cc-by

publisherhttps://link.springer.com/content/pdf/10.1007/s11357-025-01653-2.pdf

publisherhttps://link.springer.com/article/10.1007/s11357-025-01653-2/fulltext.html

repositoryhttps://real.mtak.hu/225405/1/s11357-025-01653-2.pdf

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12181582

https://doi.org/10.1007/s11357-025-01653-2

Fields of Study

0303 health sciences03 medical and health sciences

Keywords

MaleSarcopeniaAgingReceptor, IGF Type 1Mice, Inbred C57BLMiceDisease Models, AnimalMicrovesselsPhysical EnduranceAnimalsHomeostasisOriginal ArticleEndothelium, VascularInsulin-Like Growth Factor IMuscle, Skeletal