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Necroptosis induced by MLKL overexpression in liver triggers cellular senescence and leads to chronic inflammation and fibrosis

GeroScience(2025)10.1007/s11357-025-01994-ySource: DataRank Database

Necroptosis induced by MLKL overexpression in liver triggers cellular senescence and leads to chronic inflammation and fibrosis is a research paper published in GeroScience (2025). On theSindex it has a DataRank of 0.104. It has been cited 1 time.

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0.104DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 0.40)OA: hybridTopics (38)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.104

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (10)

Sunho Lee ORCID,M. Saminathan,Puvarajan Boovalingam,Kavitha Kurup ORCID,Kevin Pham ORCID

Live enrichment

PubMed:41283975 PMC:PMC12972278 OpenAlex:https://openalex.org/W4416579015

U.S. Department of Veterans Affairs

Grant: 1IK6BX005238

U.S. Department of Veterans Affairs

Grant: IK6BX006033

BLRD VA

Grant: I01 BX007006

FWCI

0.40

Citation Percentile

0.6%

Citation Trend

2026

hybridLicense: cc-by

journalhttps://link.springer.com/content/pdf/10.1007/s11357-025-01994-y.pdf

publisherhttps://link.springer.com/content/pdf/10.1007/s11357-025-01994-y.pdf

publisherhttps://link.springer.com/article/10.1007/s11357-025-01994-y

journalhttps://doi.org/10.1007/s11357-025-01994-y

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41283975

Fields of Study

Cell death mechanisms and regulationTelomeres, Telomerase, and SenescenceNuclear Structure and FunctionAnimalsNecroptosisCellular SenescenceMiceProtein KinasesInflammationHepatocytesLiverLiver CirrhosisDisease Models, AnimalMale

MeSH Terms

NecroptosisAnimalsDisease Models, AnimalInflammationLiverLiver CirrhosisMaleProtein KinasesCellular SenescenceHepatocytesMice

Keywords

NecroptosisProinflammatory cytokineInflammationProgrammed cell deathHMGB1FibrosisSenescenceApoptosisAutophagyCellular senescenceChronic InflammationInflammagingMlkl