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Decreased functional connectivity is associated with increased levels of Cerebral Spinal Fluid soluble-PDGFRβ, a marker of blood brain barrier breakdown, in older adults

Brain Imaging and Behavior(2024)10.1007/s11682-024-00912-8Source: DataRank Database

Decreased functional connectivity is associated with increased levels of Cerebral Spinal Fluid soluble-PDGFRβ, a marker of blood brain barrier breakdown, in older adults is a research paper published in Brain Imaging and Behavior (2024). On theSindex it has a DataRank of 0.224. It has been cited 3 times, with 3 citing works in its 1-hop citation network.

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0.224DataRank · unranked

Scored on demand from live citation data

Open Access3 citations · 3 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)OA: hybridTopics (59)IDs (PubMed)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 93%Citation Network 7%

Base Score Contribution

0.208

From this paper's citation signal

Citation Network Contribution

0.0165

From 1 citing papers with measurable signal

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Top 3 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 3 citers.

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Pharmaceuticals20260 citations68 referencesContributes 0.000
Tracking pericyte dysfunction in Alzheimer’s disease: The emerging role of cerebrospinal fluid platelet-derived growth factor receptor-β
Tzu Chi Medical Journal20260 citations97 referencesContributes 0.000

Authors (12)

Kimiko Fujisaki ORCID,Nancy E Ortega ORCID,Giuseppe Barisano ORCID,Abhay P. Sagare ORCID,Ioannis Pappas ORCID

Live enrichment

PubMed:39254921

NIH

Grant: 2P01AG052350

ADRC

Grant: P30AG066530

NCATS

Grant: UL1TR001855

National Institutes of Health

Grant: 3P30AG066530-04S1

Alzheimer Disease Research Center

National Institutes of Health

Grant: 3UL1TR001855-06A1S1

Southern California Clinical and Translational Science Institute

National Institutes of Health

Grant: 5P01AG052350-04

Vascular Contributions to Dementia and Genetic Risk Factors for Alzheimer's Disease

NIH HHS

Grant: S10 OD032285

NIA NIH HHS

Grant: P01 AG052350

hybridLicense: cc-by

publisherhttps://link.springer.com/content/pdf/10.1007/s11682-024-00912-8.pdf

publisherhttps://link.springer.com/article/10.1007/s11682-024-00912-8/fulltext.html

repositoryhttps://escholarship.org/content/qt9546f52n/qt9546f52n.pdf

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11680618/pdf/11682_2024_Article_912.pdf

https://doi.org/10.1007/s11682-024-00912-8

Fields of Study

03 medical and health sciences0302 clinical medicineHumansFemaleMaleAgedMagnetic Resonance ImagingBlood-Brain BarrierBrainCognitive DysfunctionBiomarkersReceptor, Platelet-Derived Growth Factor betaDefault Mode NetworkMiddle AgedNeural PathwaysAged, 80 and overConnectome

MeSH Terms

HumansFemaleMaleAgedMagnetic Resonance ImagingBlood-Brain BarrierBrainCognitive DysfunctionBiomarkersReceptor, Platelet-Derived Growth Factor betaDefault Mode NetworkMiddle AgedNeural PathwaysAged, 80 and overConnectome

Keywords

MaleBBB breakdown610Default mode network (DMN)ArticleReceptor, Platelet-Derived Growth Factor betaNeural Pathways80 and overConnectomeHumansCognitive DysfunctionAgedAged, 80 and overResearchBrainDefault Mode Network600Middle AgedMagnetic Resonance ImagingPlatelet-Derived Growth Factor betaCognitive impairmentBlood-Brain BarrierFemaleSoluble platelet-derived growth factor receptor-β (sPDGFRβ)Resting-state functional magnetic resonance imaging (rsfMRI)BiomarkersReceptor