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Suppression of Wnt/β-Catenin Signaling Is Associated with Downregulation of Wnt1, PORCN, and Rspo2 in Alzheimer’s Disease

Molecular Neurobiology(2022)10.1007/s12035-022-03065-1Source: DataRank Database

Suppression of Wnt/β-Catenin Signaling Is Associated with Downregulation of Wnt1, PORCN, and Rspo2 in Alzheimer’s Disease is a research paper published in Molecular Neurobiology (2022). On theSindex it has a DataRank of 0. It has been cited 22 times.

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0DataRank · unranked

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Open Access22 citations

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doi

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 1.76)OA: greenTopics (55)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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Authors (10)

Na Wang ORCID,Jing Zhao ORCID,Yingxue Ren ORCID,Wenyan Lü,Tadafumi C. Ikezu ORCID

Live enrichment

PubMed:36215026 PMC:PMC9795414 OpenAlex:https://openalex.org/W4304117543

NIH

Grant: R21AG065653

NIH

Grant: U19AG069701

Florida Department of State

Grant: 9AZ09

National Institutes of Health

Grant: 1R21AG065653-01A1

Novel Wnt activators for Alzheimer's disease therapy

National Institutes of Health

Grant: 1U19AG069701-01

Biology and pathobiology of apoE in aging and Alzheimer's disease

FWCI

1.76

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

greenLicense: Springer Nature TDM

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC9795414/pdf/nihms-1859521.pdf

publisherhttps://link.springer.com/content/pdf/10.1007/s12035-022-03065-1.pdf

publisherhttps://link.springer.com/article/10.1007/s12035-022-03065-1/fulltext.html

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9795414

Fields of Study

Alzheimer's disease research and treatmentsWnt/β-catenin signaling in development and cancerGenetics and Neurodevelopmental DisordersMedicineBiology0301 basic medicine0303 health sciences03 medical and health sciencesAnimalsHumansMiceAcyltransferasesAlzheimer DiseaseApolipoprotein E4Down-RegulationMembrane ProteinsWnt Signaling PathwayIntercellular Signaling Peptides and ProteinsWnt1 ProteinR-Spondins

MeSH Terms

R-SpondinsAcyltransferasesAlzheimer DiseaseAnimalsHumansMembrane ProteinsDown-RegulationIntercellular Signaling Peptides and ProteinsWnt1 ProteinMiceApolipoprotein E4Wnt Signaling Pathway

Keywords

Wnt signaling pathwayBiologyBeta-cateninCell biologyCancer researchSignal transductionAlzheimer’s diseaseWnt signalingWnt1Apoe4PorcnRspo2R-SpondinsApolipoprotein E4Down-RegulationMembrane ProteinsWnt1 ProteinMiceAlzheimer DiseaseAnimalsHumansIntercellular Signaling Peptides and ProteinsAcyltransferases

Additional file 1 of APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids

10.6084/m9.figshare.24002714.v1figshare

Additional file 1 of APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids

10.6084/m9.figshare.24002714figshare

Suppression of Wnt/β-Catenin Signaling Is Associated with Downregulation of Wnt1, PORCN, and Rspo2 in Alzheimer’s Disease

FAIR Checklist

Authors (10)

Funding (5 grants)

Impact

Open Access

Topics

Linked Datasets (2)

Annotations (Europe PMC)