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Evaluation of Hedgehog Pathway Inhibitors as a Therapeutic Option for Uterine Leiomyosarcoma Using the Xenograft Model

Reproductive Sciences(2021)10.1007/s43032-021-00731-ySource: DataRank Database

Evaluation of Hedgehog Pathway Inhibitors as a Therapeutic Option for Uterine Leiomyosarcoma Using the Xenograft Model is a research paper published in Reproductive Sciences (2021). On theSindex it has a DataRank of 0. It has been cited 10 times.

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Open Access10 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (10 grants)Impact (FWCI 0.67)OA: hybridTopics (67)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Mara Ulin ORCID,Mohamed Ali ORCID,Ayman Al‐Hendy ORCID,Kátia Cândido Carvalho ORCID,Qiwei Yang ORCID

Live enrichment

PubMed:34642915 PMC:PMC8863774 OpenAlex:https://openalex.org/W3207534735

Fundação de Amparo à Pesquisa do Estado de São Paulo

Grant: FAPESP 2017/24448-1

National Institutes of Health

Grant: RO1 HD094378

National Institutes of Health

Grant: RO1 ES028615

National Institutes of Health

Grant: U54 MD007602

National Institutes of Health

Grant: RO1HD094380

NICHD NIH HHS

Grant: R01 HD094380

National Institutes of Health

Grant: 3R01HD094378-02S1

Hypovitaminosis D promotes MED12-associated genomic instability in uterine fibroids

National Institutes of Health

Grant: 5U54MD007602-35

Center for Translational Research in Health Disparities

National Institutes of Health

Grant: 5R01HD094380-04

Mechanisms of actions(s) of simvastatin in uterine leiomyoma

National Institutes of Health

Grant: 1R01ES028615-01

Gene X Environment Interactions in the Pathogenesis of Uterine Fibroids

FWCI

0.67

Citation Percentile

0.7%

Citation Trend

2022

2023

2024

2025

hybridLicense: cc-by

journalhttps://link.springer.com/content/pdf/10.1007/s43032-021-00731-y.pdf

publisherhttps://link.springer.com/content/pdf/10.1007/s43032-021-00731-y.pdf

publisherhttps://link.springer.com/article/10.1007/s43032-021-00731-y/fulltext.html

journalhttps://doi.org/10.1007/s43032-021-00731-y

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34642915

Fields of Study

Hedgehog Signaling Pathway StudiesChromatin Remodeling and CancerTeratomas and Epidermoid Cysts0301 basic medicine03 medical and health sciences0302 clinical medicine

MeSH Terms

AnimalsBiphenyl CompoundsFemaleHumansLeiomyosarcomaMice, NudePhenotypePyridinesPyrimidinesUterine NeoplasmsSignal TransductionXenograft Model Antitumor AssaysCell Line, TumorMiceHedgehog Proteins

Keywords

GLI1Hedgehog signaling pathwayVismodegibHedgehogMedicineCancer researchDownregulation and upregulationOncologyInternal medicinePharmacologyIn vivoEndocrinologySignal transductionBiologyGeneCell biologyUterine LeiomyosarcomaHedgehog SignalingSmo InhibitorGli InhibitorLeiomyosarcomaPyridinesMice, NudeBiochemistryMiceCell Line, TumorBiochemistry, Genetics and Molecular BiologyHealth SciencesAnimalsHumansHedgehog ProteinsMolecular BiologyChromatin Remodeling in Cancer and DevelopmentBiphenyl CompoundsLife SciencesXenograft Model Antitumor AssaysGynecologic Oncology: Original ArticlePhenotypePyrimidinesHedgehog Signaling in Development and CancerUterine NeoplasmsFemaleSurgeryDiagnosis and Management of Fetal and Neonatal TumorsTumor SuppressorBiotechnology

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being