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A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression

Acta Biomaterialia(2024)10.1016/j.actbio.2024.07.036Source: DataRank Database

A three-dimensional valve-on-chip microphysiological system implicates cell cycle progression, cholesterol metabolism and protein homeostasis in early calcific aortic valve disease progression is a research paper published in Acta Biomaterialia (2024). On theSindex it has a DataRank of 0. It has been cited 10 times.

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Open Access10 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (16 grants)Impact (FWCI 2.94)OA: greenTopics (50)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (19)

Alan E. Woessner ORCID,Laís Ferreira,Christine Shamblin,Gustavo Vaca-Diez ORCID,Amanda Walls

Live enrichment

PubMed:39084496 PMC:PMC11702842 OpenAlex:https://openalex.org/W4401155094

National Science Foundation

Grant: CBET-1846853

National Science Foundation

Grant: CMMI-1452943

American Heart Association Inc

Grant: 19PRE34370061

National Institutes of Health

Grant: P20GM139768

National Institutes of Health

Grant: 1R15AI169564

National Institutes of Health

Grant: R01AG056560

National Institutes of Health

Grant: R01EB031032

National Institutes of Health

Grant: 1R01HL165251

National Institutes of Health

Grant: S10OD026736

National Institutes of Health

Grant: P20GM121293

National Institutes of Health

Grant: R24GM137786

NHLBI NIH HHS

Grant: R01 HL165251

NIAID NIH HHS

Grant: R15 AI169564

National Science Foundation

American Heart Association Inc

National Institutes of Health

FWCI

2.94

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11702842/pdf/nihms-2013364.pdf

publisherhttps://api.elsevier.com/content/article/PII:S1742706124004173?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1742706124004173?httpAccept=text/plain

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11702842/

Fields of Study

Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment ApproachesElectrospun Nanofibers in Biomedical ApplicationsAortic ValveCalcinosisAnimalsCholesterolAortic Valve StenosisLab-On-A-Chip DevicesCell CycleHumansSwineHomeostasisDisease ProgressionHydrogelsCoculture TechniquesExtracellular MatrixEndothelial CellsMicrophysiological SystemsAortic Valve, Calcification of

MeSH Terms

Microphysiological SystemsAnimalsAortic ValveAortic Valve StenosisCalcinosisCell CycleCholesterolExtracellular MatrixHomeostasisHumansSwineDisease ProgressionCoculture TechniquesHydrogelsEndothelial CellsLab-On-A-Chip Devices

Keywords

Aortic valveDiseaseCholesterolInternal medicineCardiologyHomeostasisMedicineCancer researchProtein expressionMultiphoton MicroscopyMicrophysiological SystemOrgan-on-chipCollagen-gag HydrogelValve Cell Metabolism

Sustainable Development Goals

SDG 0: Zero hunger