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Pleiotropic Effects of Trait-Associated Genetic Variation on DNA Methylation: Utility for Refining GWAS Loci

The American Journal of Human Genetics(2017)10.1016/j.ajhg.2017.04.013Source: DataRank Database

Pleiotropic Effects of Trait-Associated Genetic Variation on DNA Methylation: Utility for Refining GWAS Loci is a research paper published in The American Journal of Human Genetics (2017). On theSindex it has a DataRank of 3.6. It has been cited 100 times, with 79 citing works in its 1-hop citation network.

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3.6DataRank · unranked

Scored on demand from live citation data

100 citations · 79 citing works in its network

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Linked data & code

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 5.90)OA: hybridTopics (60)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 19%Citation Network 81%

Base Score Contribution

0.692

From this paper's citation signal

Citation Network Contribution

2.9

From 72 citing papers with measurable signal

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Authors (5)

Mike Weedon,Nicholas Bray,Michael O’Donovan,Jonathan Mill ORCID,Eilis Hannon

Live enrichment

PubMed:28528868 PMC:PMC5473725 OpenAlex:https://openalex.org/W2613373507

UK Medical Research Council

Grant: MR/K013807/1

Methylomic profiling in schizophrenia: towards an integrated genetic-epigenetic approach

Medical Research Council

Grant: MR/L010305/1

Medical Research Council

Grant: MR/L010674/1

Medical Research Council

Grant: MR/L010674/2

Wellcome Trust

Grant: unidentified

unidentified

FWCI

5.90

Citation Percentile

1.0%

Citation Trend

2017

2018

2019

2020

2021

2022

2023

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2025

2026

hybridLicense: cc-by

journalhttp://www.cell.com/article/S0002929717301581/pdf

publisherhttp://www.cell.com/article/S0002929717301581/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0002929717301581?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0002929717301581?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.ajhg.2017.04.013

Fields of Study

Epigenetics and DNA MethylationGenetic Syndromes and ImprintingGenetic Associations and Epidemiology0301 basic medicine03 medical and health sciences

MeSH Terms

BrainCrohn DiseaseFetusHumansMigraine DisordersRepressor ProteinsGenetic VariationDNA MethylationQuantitative Trait, HeritableQuantitative Trait LociBasic Helix-Loop-Helix Transcription FactorsBasic Helix-Loop-Helix ProteinsGenome-Wide Association StudyMendelian Randomization AnalysisGenetic Pleiotropy

Keywords

Genome-wide association studyBiologyExpression quantitative trait lociQuantitative trait locusGeneticsGenetic associationMendelian randomizationGenetic architectureDNA methylationGeneSingle-nucleotide polymorphismComputational biologyGene expressionGenetic variantsGenotypeBrainBloodDiseaseEpigeneticsGwasPleiotropyComplex TraitBasic Helix-Loop-Helix ProteinsMigraine DisordersQuantitative Trait Loci610Quantitative TraitFetusQuantitative Trait, HeritableCrohn DiseaseReportBasic Helix-Loop-Helix Transcription FactorsHumansHeritableGenetic VariationGenetic PleiotropyMendelian Randomization AnalysisWessex Classification Subject Headings::Oncology. Pathology.::GeneticsR1Repressor Proteins

Sustainable Development Goals

SDG 3: 3. Good healthSDG 4: 4. Education