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Local ancestry-informed GWAS of warfarin dose requirement in African Americans identifies a CYP2C19 splicing QTL

The American Journal of Human Genetics(2025)10.1016/j.ajhg.2025.09.006Source: DataRank Database

Local ancestry-informed GWAS of warfarin dose requirement in African Americans identifies a CYP2C19 splicing QTL is a research paper published in The American Journal of Human Genetics (2025). On theSindex it has a DataRank of 0.104. It has been cited 1 time, with 1 citing works in its 1-hop citation network.

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0.104DataRank · unranked

Scored on demand from live citation data

1 citations · 1 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.38)OA: closedTopics (31)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.104

From this paper's citation signal

Citation Network Contribution

From 0 citing papers with measurable signal

This paper's DataRank is currently driven only by its base citation score. None of the citing papers had measurable citation signal.

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Authors (11)

Cristina Alarcón ORCID,Edith A. Nutescu ORCID,Travis J. O’Brien ORCID,Matthew Tuck ORCID,Li Gong ORCID

Live enrichment

PubMed:41027428 OpenAlex:https://openalex.org/W4414751578

National Institute on Minority Health and Health Disparities

Grant: 1U54MD010723-01

American Heart Association Inc

Grant: 10GRNT3750024

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: U2CDK129917

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: TL1DK132769

FWCI

0.38

Citation Percentile

0.6%

Citation Trend

2025

closedLicense: http://www.elsevier.com/open-access/userlicense/1.0/

publisherhttps://api.elsevier.com/content/article/PII:S0002929725003623?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0002929725003623?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.ajhg.2025.09.006

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41027428

Fields of Study

Receptor Mechanisms and SignalingPharmacogenetics and Drug MetabolismRenin-Angiotensin System Studies

MeSH Terms

WhiteAdultAgedAnticoagulantsBlack or African AmericanFemaleGenotypeHumansMaleMiddle AgedPharmacogeneticsRNA SplicingWarfarinPolymorphism, Single NucleotideQuantitative Trait LociGenome-Wide Association StudyCytochrome P-450 CYP2C9Cytochrome P-450 CYP2C19

Keywords

PharmacogenomicsCYP2C19WarfarinVKORC1Single-nucleotide polymorphismCYP2C9CohortGenome-wide association studyPharmacogeneticsLocus (genetics)