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The Otto Aufranc Award: DNMT3A-PPARγ Signaling Is a Key Epigenetic Mechanism of Hip Osteoarthritis Disease: A Potential Therapeutic Target

The Journal of Arthroplasty(2025)10.1016/j.arth.2025.03.079Source: DataRank Database

The Otto Aufranc Award: DNMT3A-PPARγ Signaling Is a Key Epigenetic Mechanism of Hip Osteoarthritis Disease: A Potential Therapeutic Target is a research paper published in The Journal of Arthroplasty (2025). On theSindex it has a DataRank of 0.208. It has been cited 3 times.

N/A

0.208DataRank · unranked

Scored on demand from live citation data

Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 3.28)OA: greenTopics (33)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.208

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (6)

Jie Shen ORCID,Robert H. Brophy ORCID,John C. Clohisy ORCID,Regis J. O’Keefe ORCID,Cecilia Pascual‐Garrido ORCID

Live enrichment

PubMed:40633988 OpenAlex:https://openalex.org/W4411968418

NIH

Grant: 1K08AR077740-01

NIAMS NIH HHS

Grant: K08 AR077740

Hope Center for Neurological Disorders, Washington University in St. Louis

Orthopaedic Research and Education Foundation

FWCI

3.28

Citation Percentile

0.9%

Citation Trend

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC13078344/

publisherhttps://api.elsevier.com/content/article/PII:S088354032500316X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S088354032500316X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.arth.2025.03.079

Fields of Study

Hip disorders and treatmentsOsteoarthritis Treatment and MechanismsBone and Joint Diseases

MeSH Terms

DNA Methyltransferase 3ACells, CulturedDNA (Cytosine-5-)-MethyltransferasesFemaleHumansMaleMiddle AgedOsteoarthritis, HipSignal TransductionChondrocytesEpigenesis, GeneticPPAR gammaInterleukin-1beta

Keywords

OsteoarthritisChondrocyteInternal medicineCartilageMedicineFemoroacetabular impingementPeroxisome proliferator-activated receptorEndocrinologyChemistryCancer researchReceptorPathologyAnatomyPhysical therapyDNA methylationChondrocytesHip

Sustainable Development Goals

SDG 0: Good health and well-being