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Inhibition of ELOVL6 activity impairs mitochondrial respiratory function and inhibits tumor progression in FGFR3-mutated bladder cancer cells

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease(2025)10.1016/j.bbadis.2025.168023Source: DataRank Database

Inhibition of ELOVL6 activity impairs mitochondrial respiratory function and inhibits tumor progression in FGFR3-mutated bladder cancer cells is a research paper published in Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2025). On theSindex it has a DataRank of 0.245. It has been cited 4 times, with 4 citing works in its 1-hop citation network.

N/A

0.245DataRank · unranked

Scored on demand from live citation data

4 citations · 4 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 2.37)OA: hybridTopics (32)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 99%Citation Network 1%

Base Score Contribution

0.241

From this paper's citation signal

Citation Network Contribution

3.49 × 10⁻³

From 1 citing papers with measurable signal

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Top 4 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 4 citers.

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Current Medical Science20260 citations39 referencesContributes 0.000
Dysregulation of Human ClpP Using Small Molecules with Piperazine-Based Scaffold for Diffuse Intrinsic Pontine Glioma Therapy Validated by Patient-Derived Tumor Organoids
Journal of Medicinal Chemistry20260 citations64 referencesContributes 0.000

Authors (24)

Shiho Hasebe,Takashi Matsuzaka,Akio Hayashi,Hiroshi Ohno ORCID,Kaori Motomura

Live enrichment

PubMed:40835210 OpenAlex:https://openalex.org/W4413275816

Japan Agency for Medical Research and Development

Grant: 16gm0910003h0002

Japan Agency for Medical Research and Development

Grant: 22H00474

Japan Agency for Medical Research and Development

Grant: 20K21643

Japan Agency for Medical Research and Development

Grant: 24K02851

Cancer Research Institute

Ministry of Education, Culture, Sports, Science and Technology

Kanazawa University

FWCI

2.37

Citation Percentile

0.9%

Citation Trend

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1016/j.bbadis.2025.168023

publisherhttps://doi.org/10.1016/j.bbadis.2025.168023

publisherhttps://api.elsevier.com/content/article/PII:S0925443925003710?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0925443925003710?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40835210

Fields of Study

Cancer, Lipids, and MetabolismFibroblast Growth Factor ResearchFatty Acid Research and Health

MeSH Terms

Fatty Acid ElongasesAnimalsUrinary Bladder NeoplasmsFemaleHumansMaleMitochondriaMutationOxidative PhosphorylationGene Expression Regulation, NeoplasticDisease ProgressionCell Line, TumorCell ProliferationMiceReceptor, Fibroblast Growth Factor, Type 3

Keywords

Cancer researchBiologyCancerFunction (biology)MitochondrionInternal medicineEndocrinologyMedicineCell biologyExtracellular matrix (ECM)Fibroblast Growth Factor Receptor 3 (Fgfr3)Bladder Cancer (Bc)Elovl Fatty Acid Elongase 6 (Elovl6)Mitochondrial Oxidative Phosphorylation (Oxphos)

Sustainable Development Goals

SDG 0: Good health and well-being

Inhibition of ELOVL6 activity impairs mitochondrial respiratory function and inhibits tumor progression in FGFR3-mutated bladder cancer cells

FAIR Checklist

DataRank Breakdown

Top 4 citers driving the network score

Authors (24)

Funding (7 grants)

Impact

Open Access

Topics