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A critical role for Macrophage-derived Cysteinyl-Leukotrienes in HIV-1 induced neuronal injury

Brain Behavior and Immunity(2024)10.1016/j.bbi.2024.02.023Source: DataRank Database

A critical role for Macrophage-derived Cysteinyl-Leukotrienes in HIV-1 induced neuronal injury is a research paper published in Brain Behavior and Immunity (2024). On theSindex it has a DataRank of 0.183. It has been cited 2 times, with 2 citing works in its 1-hop citation network.

N/A

0.183DataRank · unranked

Scored on demand from live citation data

Open Access2 citations · 2 citing works in its network

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Cite:

Linked data & code

geo gen refseq

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (14 grants)Impact (FWCI 0.45)OA: hybridTopics (46)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 90%Citation Network 10%

Base Score Contribution

0.165

From this paper's citation signal

Citation Network Contribution

0.0187

From 2 citing papers with measurable signal

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Top 2 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 2 citers.

GPR17 in Glioblastoma: Structure, Ligand Interactions, and Therapeutic Targeting
ACS Omega20252 citations74 referencesContributes 0.015
The impact of aging on HIV-1-related neurocognitive impairment
Ageing Research Reviews20248 citations309 referencesContributes 0.007

Authors (12)

Kathryn E. Medders,Ana B. Sánchez,Rohan Shah ORCID,Cyrus M. de Rozieres,Daniel Ojeda-Juárez ORCID

Live enrichment

PubMed:38423397 PMC:PMC11173376 OpenAlex:https://openalex.org/W4392203549

National Institutes of Health

Grant: DA052209

NIMH

Grant: MH087332

NIMH

Grant: MH104131

NIMH

Grant: MH105330

NIMH

Grant: R25 MH081482

NIMH

Grant: U24MH100930

NINDS

Grant: R01 NS050621

NIMH NIH HHS

Grant: R01 MH104131

NIMH NIH HHS

Grant: R01 MH105330

NIMH NIH HHS

Grant: R01 MH087332

NIDA NIH HHS

Grant: R01 DA052209

Scripps Research

University of California, Riverside

Sanford Burnham Prebys

FWCI

0.45

Citation Percentile

0.6%

Citation Trend

2024

2025

hybridLicense: cc-by

journalhttps://doi.org/10.1016/j.bbi.2024.02.023

publisherhttps://doi.org/10.1016/j.bbi.2024.02.023

publisherhttps://api.elsevier.com/content/article/PII:S0889159124002599?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0889159124002599?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38423397

Fields of Study

HIV Research and TreatmentNeuroinflammation and Neurodegeneration MechanismsTryptophan and brain disordersMiceHumansAnimalsHIV-1MacrophagesLeukotrienesNeuronsp38 Mitogen-Activated Protein KinasesMice, TransgenicHIV InfectionsCysteine

MeSH Terms

AnimalsCysteineHumansMacrophagesMice, TransgenicNeuronsLeukotrienesHIV-1HIV Infectionsp38 Mitogen-Activated Protein KinasesMice

Keywords

Neurotoxicityp38 mitogen-activated protein kinasesMAPK/ERK pathwayCell biologyBiologyProtein kinase ASignal transductionKinaseNeurosciencePharmacologyMedicineToxicityInternal medicineMacrophagesHIVKnockoutp38 MAPKErk1/2 SignalingCysteinyl LeukotrienesBehavior DeficitsHivgp120-transgenic, Hiv Associated Neurocognitive Disorder

Sustainable Development Goals

SDG 0: Good health and well-being