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Endothelial MAP2K1 mutations in arteriovenous malformation activate the RAS/MAPK pathway

Biochemical and Biophysical Research Communications(2020)10.1016/j.bbrc.2020.06.022Source: DataRank Database

Endothelial MAP2K1 mutations in arteriovenous malformation activate the RAS/MAPK pathway is a research paper published in Biochemical and Biophysical Research Communications (2020). On theSindex it has a DataRank of 0. It has been cited 40 times.

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Open Access40 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: bronzeTopics (35)IDs (PubMed, PMC)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Dennis J. Konczyk ORCID,Christopher L. Sudduth ORCID,Jeremy A. Goss ORCID,Arin K. Greene ORCID,Patrick Smits ORCID

Live enrichment

PubMed:32703450 PMC:PMC7443257

NHLBI NIH HHS

Grant: R01 HL127030

NHLBI NIH HHS

Grant: R01 HL141917

NICHD NIH HHS

Grant: R01 HD093735

NCATS NIH HHS

Grant: UL1 TR001863

National Institutes of Health

Grant: 5R01HD093735-05

Determining the pathophysiology of pediatric arteriovenous malformation

National Institutes of Health

bronzeLicense: Elsevier TDM

https://doi.org/10.1016/j.bbrc.2020.06.022

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443257

https://pubmed.ncbi.nlm.nih.gov/32703450

https://dx.doi.org/10.1016/j.bbrc.2020.06.022

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Cells, CulturedEndothelial CellsHumansArteriovenous Malformationsras ProteinsMAP Kinase Kinase 1Mitogen-Activated Protein KinasesSignal TransductionMAP Kinase Signaling SystemEnzyme ActivationPoint MutationHuman Umbilical Vein Endothelial Cells

Keywords

MechanismSignalingMAPKVascularMalformationRasArteriovenous MalformationMap2k1MAP Kinase Signaling SystemMAP Kinase Kinase 1Endothelial CellsArteriovenous MalformationsEnzyme ActivationHuman Umbilical Vein Endothelial Cellsras ProteinsHumansPoint MutationMitogen-Activated Protein KinasesCells, CulturedSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good health