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4-Aminoquinolines modulate RNA structure and function: Pharmacophore implications of a conformationally restricted polyamine

Biochemical and Biophysical Research Communications(2022)10.1016/j.bbrc.2022.12.080Source: DataRank Database

4-Aminoquinolines modulate RNA structure and function: Pharmacophore implications of a conformationally restricted polyamine is a research paper published in Biochemical and Biophysical Research Communications (2022). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Scored on demand from live citation data

Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (10 grants)Impact (FWCI 0.16)OA: greenTopics (53)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Mason Myers,Danushika Herath ORCID,Ali H. Aldhumani ORCID,Hannah Boesger ORCID,Jennifer V. Hines ORCID

Live enrichment

PubMed:36630735 PMC:PMC10473465 OpenAlex:https://openalex.org/W4313234041

National Institutes of Health

Grant: 1C06 RR14575-01

National Institutes of Health

Grant: 1R15GM132841

NCRR NIH HHS

Grant: C06 RR014575

NIGMS NIH HHS

Grant: R15 GM132841

National Institutes of Health

Grant: 1C06RR014575-01

RENOVATION OF BIOCHEMISTRY LABORATORIES

National Institutes of Health

Grant: 2R15GM132841-02

R15 AREA: Optimizing allosteric modulation of noncoding regulatory RNA function

Ohio Supercomputer Center

Ohio University Department of Chemistry and Biochemistry

Ohio University

Foundation for the National Institutes of Health

FWCI

0.16

Citation Percentile

0.4%

Citation Trend

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10473465/pdf/nihms-1925752.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0006291X22017594?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0006291X22017594?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10473465

Fields of Study

RNA and protein synthesis mechanismsRNA modifications and cancerDNA and Nucleic Acid Chemistry0301 basic medicine0303 health sciences03 medical and health sciencesHumansPolyaminesPharmacophoreRiboswitchHydroxychloroquineRNA, ViralCOVID-19SARS-CoV-2AminoquinolinesRNA, BacterialNucleic Acid Conformation

MeSH Terms

COVID-19SARS-CoV-2PharmacophoreAminoquinolinesHumansHydroxychloroquineNucleic Acid ConformationPolyaminesRNA, BacterialRNA, ViralRiboswitch

Keywords

RiboswitchPharmacophoreRNAPolyamineChemistryNucleic acid structureRNA editingComputational biologyBiochemistryBiologyNon-coding RNARNA bindingdrug discovery4-AminoquinolineT-box RiboswitchSars-cov-2 Stem-loop Ii Motif (S2m)SARS-CoV-2COVID-19RNA, BacterialPolyaminesAminoquinolinesHumansRNA, ViralNucleic Acid ConformationHydroxychloroquine

Sustainable Development Goals

SDG 0: Good health and well-being