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Multidimensional screening of pancreatic cancer spheroids reveals vulnerabilities in mitotic and cell-matrix adhesion signaling that associate with metastatic progression and decreased patient survival

Biochemical and Biophysical Research Communications(2024)10.1016/j.bbrc.2024.149575Source: DataRank Database

Multidimensional screening of pancreatic cancer spheroids reveals vulnerabilities in mitotic and cell-matrix adhesion signaling that associate with metastatic progression and decreased patient survival is a research paper published in Biochemical and Biophysical Research Communications (2024). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)Impact (FWCI 0.35)OA: hybridTopics (42)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Farhana Runa,Jannatul F. Shoma ORCID,Audrey Todd,Matthew Wallace ORCID,Natan Roberto de Barros ORCID

Live enrichment

PubMed:38382357 PMC:PMC10983059 OpenAlex:https://openalex.org/W4391573872

National Institute of General Medical Sciences

Grant: 2SC1GM121182

NIGMS NIH HHS

Grant: SC1 GM121182

National Institute of General Medical Sciences

FWCI

0.35

Citation Percentile

0.6%

Citation Trend

2025

2026

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.bbrc.2024.149575

HYBRIDhttps://doi.org/10.1016/j.bbrc.2024.149575

publisherhttps://doi.org/10.1016/j.bbrc.2024.149575

publisherhttps://api.elsevier.com/content/article/PII:S0006291X24001104?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0006291X24001104?httpAccept=text/plain

Fields of Study

Pancreatic and Hepatic Oncology ResearchCancer Cells and MetastasisCancer Genomics and DiagnosticsMedicineBiologyHumansProto-Oncogene Proteins p21(ras)Early Detection of CancerPancreatic NeoplasmsCarcinoma, Pancreatic DuctalCollagenCell-Matrix JunctionsFocal Adhesion Protein-Tyrosine KinasesCell Line, Tumor

MeSH Terms

CollagenHumansPancreatic NeoplasmsProto-Oncogene Proteins p21(ras)Carcinoma, Pancreatic DuctalCell-Matrix JunctionsCell Line, TumorFocal Adhesion Protein-Tyrosine KinasesEarly Detection of Cancer

Keywords

SpheroidFocal adhesionCancer researchKRASStromal cellBiologyPathologyCancerChemistryCell biologySignal transductionMedicineCell cultureColorectal cancerMitosisCell adhesionIntegrinsPancreatic cancerSpheroids

Sustainable Development Goals

SDG 0: Good health and well-being