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The effects of anthracycline drugs on the conformational distribution of mouse P-glycoprotein explains their transport rate differences

Biochemical Pharmacology(2020)10.1016/j.bcp.2020.113813Source: DataRank Database

The effects of anthracycline drugs on the conformational distribution of mouse P-glycoprotein explains their transport rate differences is a research paper published in Biochemical Pharmacology (2020). On theSindex it has a DataRank of 0. It has been cited 21 times.

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Open Access21 citations

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Enrichment:Funding (6 grants)Impact (FWCI 0.91)OA: greenTopics (55)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Krishna P. Sigdel ORCID,Katherine G. Schaefer ORCID,Gershon A.K. Mensah ORCID,Gavin M. King ORCID,Arthur G. Roberts ORCID

Live enrichment

PubMed:31954717 PMC:PMC8262137 OpenAlex:https://openalex.org/W3000741494

NCI NIH HHS

Grant: R01 CA204846

National Institutes of Health

Grant: 1R01CA204846-01A1

Overcoming Cancer Resistance Mediated by the Human MDR1 Transporter

National Science Foundation

Grant: 1054832

CAREER: Structure and Dynamical Mechanisms of Membrane Transport Proteins: New Vistas Via Ultra-stable Force Microscopy

Burroughs Wellcome Fund

National Institutes of Health

National Science Foundation

FWCI

0.91

Citation Percentile

0.8%

Citation Trend

2020

2022

2023

2024

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8262137

publisherhttps://api.elsevier.com/content/article/PII:S000629522030023X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S000629522030023X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bcp.2020.113813

Fields of Study

Drug Transport and Resistance MechanismsProtein Interaction Studies and Fluorescence AnalysisNanoparticle-Based Drug Delivery0301 basic medicine0303 health sciences03 medical and health sciencesATP Binding Cassette Transporter, Subfamily B, Member 1AnimalsAnthracyclinesAntibiotics, AntineoplasticDaunorubicinDose-Response Relationship, DrugDoxorubicinMiceProtein ConformationProtein Transport

MeSH Terms

AnimalsAntibiotics, AntineoplasticDaunorubicinDose-Response Relationship, DrugDoxorubicinProtein ConformationAnthracyclinesATP Binding Cassette Transporter, Subfamily B, Member 1Protein TransportMice

Keywords

DaunorubicinP-glycoproteinChemistryAnthracyclineTransporterATP hydrolysisEffluxDoxorubicinBiophysicsConformational changeBiochemistryLipid bilayerPharmacologyMultiple drug resistanceBiologyEnzymeCancerMembraneProtein conformationatomic force microscopy (AFM)Multidrug Resistance TransportersAnti-cancer Drug ResistanceAntibiotics, AntineoplasticDose-Response Relationship, DrugMiceProtein TransportAnimalsAnthracyclinesATP Binding Cassette Transporter, Subfamily B, Member 1

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

The effects of anthracycline drugs on the conformational distribution of mouse P-glycoprotein explains their transport rate differences

FAIR Checklist

Authors (6)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)