Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Overexpression of ABCB1 and ABCG2 contributes to reduced efficacy of the PI3K/mTOR inhibitor samotolisib (LY3023414) in cancer cell lines

Biochemical Pharmacology(2020)10.1016/j.bcp.2020.114137Source: DataRank Database

Overexpression of ABCB1 and ABCG2 contributes to reduced efficacy of the PI3K/mTOR inhibitor samotolisib (LY3023414) in cancer cell lines is a research paper published in Biochemical Pharmacology (2020). On theSindex it has a DataRank of 0. It has been cited 25 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access25 citations

Download PDF

Cite:

Linked data & code

gen nct pdb doi

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 1.37)OA: greenTopics (38)IDs (PubMed, PMC, OpenAlex)Annotations (4)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (8)

Cheng‐Yu Hung ORCID,Sabrina Lusvarghi ORCID,Yang-Hui Huang,Pin-Jung Tseng,Tai‐Ho Hung ORCID

Live enrichment

PubMed:32634436 PMC:PMC7606332 OpenAlex:https://openalex.org/W3040191052

Intramural NIH HHS

Grant: Z01 BC010030

Intramural NIH HHS

Grant: ZIA BC010030

Chang Gung Medical Foundation

Ministry of Science and Technology, Taiwan

National Institutes of Health

FWCI

1.37

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

2026

greenLicense: https://www.elsevier.com/legal/tdmrep-license

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7606332

publisherhttps://api.elsevier.com/content/article/PII:S0006295220303737?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0006295220303737?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bcp.2020.114137

Fields of Study

Drug Transport and Resistance MechanismsHIV/AIDS drug development and treatmentPharmacological Effects and Toxicity Studies

MeSH Terms

ATP Binding Cassette Transporter, Subfamily G, Member 2Phosphoinositide-3 Kinase InhibitorsCell SurvivalHumansNeoplasm ProteinsPyridinesQuinolonesATP Binding Cassette Transporter, Subfamily BCell Culture TechniquesDrug Resistance, NeoplasmPhosphatidylinositol 3-KinasesCell Line, TumorHEK293 CellsTOR Serine-Threonine Kinases

Keywords

Abcg2PI3K/AKT/mTOR pathwayEffluxCancer cellIn silicoATP-binding cassette transporterTransporterPharmacologyMultiple drug resistanceDrug resistanceBiologyCancer researchCancerChemistryCell biologyBiochemistrySignal transductionMultidrug resistanceAbcb1Pi3k/mtorLy3023414

Sustainable Development Goals

SDG 0: Good health and well-being

Overexpression of ABCB1 and ABCG2 contributes to reduced efficacy of the PI3K/mTOR inhibitor samotolisib (LY3023414) in cancer cell lines

FAIR Checklist

Authors (8)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)