Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

(+)-Catharanthine potentiates the GABAA receptor by binding to a transmembrane site at the β(+)/α(-) interface near the TM2-TM3 loop

Biochemical Pharmacology(2022)10.1016/j.bcp.2022.114993Source: DataRank Database

(+)-Catharanthine potentiates the GABAA receptor by binding to a transmembrane site at the β(+)/α(-) interface near the TM2-TM3 loop is a research paper published in Biochemical Pharmacology (2022). On theSindex it has a DataRank of 0.292. It has been cited 6 times.

N/A

0.292DataRank · unranked

Scored on demand from live citation data

Open Access6 citations

Download PDF

Cite:

Linked data & code

pdb

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)OA: greenTopics (24)IDs (PubMed, PMC)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.292

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

Learn more about DataRank methodology →

Authors (11)

Cecilia M. Borghese ORCID,Allison L. Germann ORCID,Spencer R. Pierce ORCID,Alessandro Bonardi ORCID,Alessio Nocentini ORCID

Live enrichment

PubMed:35304861 PMC:PMC9178925

NIGMS NIH HHS

Grant: R01 GM108580

NIGMS NIH HHS

Grant: R35 GM140947

NIAAA NIH HHS

Grant: U24 AA025479

National Institutes of Health

Grant: 5R35GM140947-05

GABAA receptors: function, physiology and involvement in anesthesia

National Institutes of Health

Grant: 5U24AA025479-03

Integrative Neuroscience Initiative on Alcoholism

National Institutes of Health

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9178925

publisherhttps://api.elsevier.com/content/article/PII:S0006295222000879?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0006295222000879?httpAccept=text/plain

repositoryhttps://hdl.handle.net/2158/1289762

https://doi.org/10.1016/j.bcp.2022.114993

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

gamma-Aminobutyric AcidVinca AlkaloidsEtomidateReceptors, GABA-ABinding SitesMolecular Docking SimulationNeurosteroids

Keywords

ElectrophysiologyMolecular dockingMolecular dynamicsPositive Allosteric ModulatorsCoronaridine Congeners(+)-CatharanthineMolecular Docking SimulationBinding Sites(+)-Catharanthine; Coronaridine congeners; Electrophysiology; Molecular docking; Molecular dynamics; Positive allosteric modulators; Binding Sites; Molecular Docking Simulation; Receptors, GABA-A; Vinca Alkaloids; gamma-Aminobutyric Acid; Etomidate; NeurosteroidsEtomidateReceptors, GABA-ANeurosteroidsVinca Alkaloidsgamma-Aminobutyric Acid

(+)-Catharanthine potentiates the GABAA receptor by binding to a transmembrane site at the β(+)/α(-) interface near the TM2-TM3 loop

FAIR Checklist

DataRank Breakdown

Authors (11)

Funding (6 grants)

Open Access

Topics

Annotations (Europe PMC)