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Kinetic profiling and functional characterization of 8-phenylxanthine derivatives as A2B adenosine receptor antagonists

Biochemical Pharmacology(2022)10.1016/j.bcp.2022.115027Source: DataRank Database

Kinetic profiling and functional characterization of 8-phenylxanthine derivatives as A2B adenosine receptor antagonists is a research paper published in Biochemical Pharmacology (2022). On theSindex it has a DataRank of 0. It has been cited 9 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access9 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 1.05)OA: hybridTopics (52)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Henk de Vries ORCID,Milena Pasoli,Miranda Goudswaard,Soon‐Ai Kim,Yong‐Chul Kim ORCID

Live enrichment

PubMed:35395239 PMC:PMC9358681 OpenAlex:https://openalex.org/W4223425509

Intramural NIH HHS

Grant: ZIA DK031117

National Institutes of Health

Grant: 1ZIADK031117-26

Development Of Drugs Acting At Adenosine Receptors

FWCI

1.05

Citation Percentile

0.7%

Citation Trend

2022

2023

2024

2025

2026

hybridLicense: cc-by

journalhttps://www.sciencedirect.com/science/article/pii/S0006295222001216/pdf

publisherhttps://www.sciencedirect.com/science/article/pii/S0006295222001216/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0006295222001216?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0006295222001216?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bcp.2022.115027

Fields of Study

Adenosine and Purinergic SignalingReceptor Mechanisms and SignalingNeuropeptides and Animal Physiology0301 basic medicine0303 health sciences03 medical and health sciencesAdenosine A2 Receptor AntagonistsKineticsPurinergic P1 Receptor AntagonistsRadioligand AssayReceptor, Adenosine A2BReceptors, Purinergic P1Xanthines

MeSH Terms

KineticsRadioligand AssayXanthinesReceptors, Purinergic P1Receptor, Adenosine A2BPurinergic P1 Receptor AntagonistsAdenosine A2 Receptor Antagonists

Keywords

Adenosine receptorPharmacologyChemistryDrug discoveryLigand efficiencyAdenosineRadioligandIn vivoBinding siteReceptorComputational biologyStereochemistryBiochemistryLigand (biochemistry)BiologyAgonistBiotechnologyBinding kineticsAntagonistsRadioligand binding assayCovalent BindingA(2b) Adenosine ReceptorLabel-free Functional AssayA2B Adenosine ReceptorReceptors, Purinergic P1Receptor, Adenosine A2BArticleAdenosine A2 Receptor AntagonistsKineticsRadioligand AssayPurinergic P1 Receptor AntagonistsXanthines

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being