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Isoquinoline small molecule ligands are agonists and probe-dependent allosteric modulators of the glucagon subfamily of GPCRs

Biochemical Pharmacology(2024)10.1016/j.bcp.2024.116483Source: DataRank Database

Isoquinoline small molecule ligands are agonists and probe-dependent allosteric modulators of the glucagon subfamily of GPCRs is a research paper published in Biochemical Pharmacology (2024). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 1.01)OA: hybridTopics (39)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Phuc N. H. Trinh ORCID,Caroline A. Hick,Rebecca Ebenhoch ORCID,Herbert Nar ORCID,Dietmar Weichert ORCID

Live enrichment

PubMed:39147328 OpenAlex:https://openalex.org/W4401528367

National Health and Medical Research Council

Grant: 1155302

National Health and Medical Research Council

Grant: 1154434

National Institutes of Health

Grant: R01-GM129325

Boehringer Ingelheim International GmbH

National Institute of Allergy and Infectious Diseases

FWCI

1.01

Citation Percentile

0.8%

Citation Trend

2024

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1016/j.bcp.2024.116483

publisherhttps://doi.org/10.1016/j.bcp.2024.116483

publisherhttps://api.elsevier.com/content/article/PII:S0006295224004660?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0006295224004660?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39147328

Fields of Study

Diabetes Treatment and ManagementReceptor Mechanisms and SignalingNeuropeptides and Animal Physiology

MeSH Terms

Glucagon-Like Peptide-1 ReceptorGlucagon-Like Peptide-1 Receptor AgonistsAllosteric RegulationAnimalsCricetulusGlucagonHumansIsoquinolinesLigandsReceptors, Gastrointestinal HormoneMolecular ProbesCHO CellsReceptors, CalcitoninReceptors, GlucagonReceptors, G-Protein-CoupledSmall Molecule LibrariesHEK293 Cells

Keywords

Allosteric regulationG protein-coupled receptorReceptorChemistrySubfamilyAllosteric modulatorGlucagon receptorPeptideBiochemistryPharmacologyBiologyGlucagonHormoneCTRAllosteric modulationGiprGlp1rGcgrClass B1 Gpcrs