Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Pyridinium derivatives of 3-aminobenzenesulfonamide are nanomolar-potent inhibitors of tumor-expressed carbonic anhydrase isozymes CA IX and CA XII

Bioorganic Chemistry(2020)10.1016/j.bioorg.2020.104204Source: DataRank Database

Pyridinium derivatives of 3-aminobenzenesulfonamide are nanomolar-potent inhibitors of tumor-expressed carbonic anhydrase isozymes CA IX and CA XII is a research paper published in Bioorganic Chemistry (2020). On theSindex it has a DataRank of 0. It has been cited 37 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access37 citations

Download PDF

Cite:

Linked data & code

gen pdb doi

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 1.71)OA: greenTopics (73)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (7)

Özlen Güzel-Akdemir ORCID,Rajesh Kishore Kumar Sanku ORCID,Samson S. Russom,Bogdan I. Iorga ORCID,Claudiu T. Supuran ORCID

Live enrichment

PubMed:32891000 PMC:PMC7846937 OpenAlex:https://openalex.org/W3081248824

National Institutes of Health

Grant: R03EB026189

Türkiye Bilimsel ve Teknolojik Araştirma Kurumu

Grant: 2219/2008

Ministero dell’Istruzione, dell’Università e della Ricerca

Grant: 2017XYBP2R

Ministero dell'Istruzione dell'Università e della Ricerca

Grant: unidentified

unidentified

Edward N. and Della L. Thome Memorial Foundation

FWCI

1.71

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7846937

publisherhttps://api.elsevier.com/content/article/PII:S0045206820315017?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0045206820315017?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bioorg.2020.104204

Fields of Study

Enzyme function and inhibitionSynthesis and Catalytic ReactionsChemical Reactions and Mechanisms0301 basic medicine0303 health sciences03 medical and health sciencesAntigens, NeoplasmAntineoplastic AgentsBase SequenceCarbonic Anhydrase IXCarbonic Anhydrase InhibitorsCarbonic AnhydrasesCatalytic DomainCell Line, TumorDrug DesignDrug Screening Assays, AntitumorHumansMolecular Docking SimulationNeoplasmsProtein BindingPyridinium CompoundsSulfonamides

MeSH Terms

Carbonic Anhydrase IXAntigens, NeoplasmAntineoplastic AgentsBase SequenceCarbonic AnhydrasesCarbonic Anhydrase InhibitorsDrug Screening Assays, AntitumorHumansNeoplasmsProtein BindingPyridinium CompoundsSulfonamidesDrug DesignCatalytic DomainCell Line, TumorMolecular Docking Simulation

Keywords

Carbonic anhydraseChemistryPyridiniumIsozymeGene isoformCytosolEnzymeStereochemistryDocking (animal)Carbonic anhydrase IIBiochemistryActive siteTransmembrane proteinReceptorMedicinal chemistryInhibitorTumor GrowthSulfonamideSulfonamidesBase SequenceAntineoplastic AgentsPyridinium CompoundsMolecular Docking SimulationAntigens, NeoplasmCatalytic DomainCell Line, TumorDrug DesignNeoplasmsCarbonic anhydrase; Inhibitor; Isozyme; Pyridinium; Sulfonamide; Tumor growthHumansDrug Screening Assays, AntitumorCarbonic Anhydrase IXCarbonic Anhydrase InhibitorsCarbonic AnhydrasesProtein Binding

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Clean water and sanitation

Pyridinium derivatives of 3-aminobenzenesulfonamide are nanomolar-potent inhibitors of tumor-expressed carbonic anhydrase isozymes CA IX and CA XII

FAIR Checklist

Authors (7)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)