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Blocking potential metabolic sites on NAT to improve its safety profile while retaining the pharmacological profile

Bioorganic Chemistry(2024)10.1016/j.bioorg.2024.107489Source: DataRank Database

Blocking potential metabolic sites on NAT to improve its safety profile while retaining the pharmacological profile is a research paper published in Bioorganic Chemistry (2024). On theSindex it has a DataRank of 0.

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Open Access0 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.00)OA: greenTopics (26)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Boshi Huang ORCID,Piyusha P. Pagare ORCID,Celsey M. St. Onge ORCID,Abeje Abebayehu,James C. Gillespie ORCID

Live enrichment

PubMed:38797065 PMC:PMC11190787 OpenAlex:https://openalex.org/W4398224825

National Institute on Drug Abuse

Grant: R01DA024022

National Institute on Drug Abuse

Grant: UG3DA050311

NIDA NIH HHS

Grant: UH3 DA050311

National Institutes of Health

FWCI

0.00

Citation Percentile

0.0%

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11190787/pdf/nihms-1999300.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0045206824003948?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0045206824003948?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11190787

Fields of Study

Receptor Mechanisms and SignalingComputational Drug Discovery MethodsNeuroscience and Neuropharmacology Research

MeSH Terms

Analgesics, OpioidAnimalsDose-Response Relationship, DrugHumansMaleMorphineNarcotic AntagonistsStructure-Activity RelationshipThiophenesMolecular StructureReceptors, Opioid, muMice

Keywords

ChemistryBlocking (statistics)Safety profilePharmacologyAdverse effectComputer networkComputer scienceAntagonistMu-opioid ReceptorStructure–activity RelationshipOpioid Use Disorder

Sustainable Development Goals

SDG 0: Good health and well-being