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Novel 4-quinolone derivative inflicted cytotoxicity via intrinsic apoptotic pathway activation on human metastatic triple-negative breast cancer cells

Bioorganic Chemistry(2025)10.1016/j.bioorg.2025.109033Source: DataRank Database

Novel 4-quinolone derivative inflicted cytotoxicity via intrinsic apoptotic pathway activation on human metastatic triple-negative breast cancer cells is a research paper published in Bioorganic Chemistry (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access2 citations

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Enrichment:Funding (11 grants)Impact (FWCI 1.03)OA: hybridTopics (40)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Muhammad Shoaib Ali Gill ORCID,Nurshariza Abdullah ORCID,Denisse A. Gutiérrez ORCID,Armando Varela-Ramı́rez ORCID,Laura A. Sanchez‐Michael ORCID

Live enrichment

PubMed:41043329 PMC:PMC12677246 OpenAlex:https://openalex.org/W4414528885

The University of Texas at El Paso

Grant: 5T32GM144919\u201303

Foundation for the National Institutes of Health

Grant: 5U54MD007592

Ministry of Higher Education, Malaysia

Grant: FRGS/1/2020/STG04/MUSM/02/1

Ministry of Higher Education, Malaysia

Grant: 1R16GM149379

NIMHD NIH HHS

Grant: U54 MD007592

NIGMS NIH HHS

Grant: T32 GM144919

NIGMS NIH HHS

Grant: R16 GM149379

University of Texas at Austin

National Institute on Minority Health and Health Disparities

National Institutes of Health

Monash University Malaysia

FWCI

1.03

Citation Percentile

0.8%

Citation Trend

2026

hybridLicense: cc-by-nc-nd

journalhttps://doi.org/10.1016/j.bioorg.2025.109033

publisherhttps://doi.org/10.1016/j.bioorg.2025.109033

publisherhttps://api.elsevier.com/content/article/PII:S0045206825009137?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0045206825009137?httpAccept=text/plain

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41043329

Fields of Study

Synthesis and biological activityCancer therapeutics and mechanismsSynthesis and Biological EvaluationHumansApoptosisAntineoplastic AgentsDrug Screening Assays, AntitumorStructure-Activity RelationshipCell ProliferationTriple Negative Breast NeoplasmsMolecular StructureDose-Response Relationship, Drug4-QuinolonesCell Line, TumorFemale

MeSH Terms

Antineoplastic AgentsDose-Response Relationship, DrugDrug Screening Assays, AntitumorFemaleHumansStructure-Activity RelationshipMolecular StructureApoptosis4-QuinolonesCell Line, TumorCell ProliferationTriple Negative Breast Neoplasms

Keywords

CytotoxicityApoptosisCell cycle checkpointBreast cancerMTT assayCancer cellCell growthCell cultureIn vitroCytotoxic activityQUinolonesAnticancer AgentsAntitumor Agents

Novel 4-quinolone derivative inflicted cytotoxicity via intrinsic apoptotic pathway activation on human metastatic triple-negative breast cancer cells

FAIR Checklist

Authors (11)

Funding (11 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)