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Structural manipulation of aporphines via C10 nitrogenation leads to the identification of new 5-HT7AR ligands

Bioorganic & Medicinal Chemistry(2020)10.1016/j.bmc.2020.115578Source: DataRank Database

Structural manipulation of aporphines via C10 nitrogenation leads to the identification of new 5-HT7AR ligands is a research paper published in Bioorganic & Medicinal Chemistry (2020). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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Enrichment:Funding (3 grants)Impact (FWCI 0.44)OA: greenTopics (49)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Hari K. Namballa,Ian L. Alberts ORCID,Wayne W. Harding ORCID,Anupam Karki

Live enrichment

PubMed:32631561 PMC:PMC7340851 OpenAlex:https://openalex.org/W3033960375

NIDA NIH HHS

Grant: SC1 DA049961

National Institutes of Health

Grant: 1SC1DA049961-01

Novel anti-cocaine D1 partial agonists

National Institutes of Health

FWCI

0.44

Citation Percentile

0.6%

Citation Trend

2022

2023

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7340851

publisherhttps://api.elsevier.com/content/article/PII:S0968089620304089?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0968089620304089?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bmc.2020.115578

Fields of Study

Traditional and Medicinal Uses of AnnonaceaeAlkaloids: synthesis and pharmacologyCarbohydrate Chemistry and Synthesis0301 basic medicine0303 health sciences03 medical and health sciencesAporphinesCell LineHumansLigandsMolecular Docking SimulationMolecular StructureReceptors, SerotoninSerotonin AntagonistsStructure-Activity Relationship

MeSH Terms

AporphinesCell LineHumansLigandsReceptors, SerotoninSerotonin AntagonistsStructure-Activity RelationshipMolecular StructureMolecular Docking Simulation

Keywords

ChemistryAporphineSelectivityMoietyStereochemistrySubstituentReceptorOrganic chemistryAlkaloidBiochemistryDopamineSerotoninSARCNS5-Ht(1a)5-Ht(7)Molecular Docking SimulationStructure-Activity RelationshipAporphinesMolecular StructureReceptors, SerotoninHumansSerotonin AntagonistsLigandsCell Line

Structural manipulation of aporphines via C10 nitrogenation leads to the identification of new 5-HT7AR ligands

FAIR Checklist

Authors (4)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)