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Synthetic fluorescent MYC probe: Inhibitor binding site elucidation and development of a high-throughput screening assay

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2021.116246Source: DataRank Database

Synthetic fluorescent MYC probe: Inhibitor binding site elucidation and development of a high-throughput screening assay is a research paper published in Bioorganic & Medicinal Chemistry (2021). On theSindex it has a DataRank of 0. It has been cited 8 times.

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0DataRank · unranked

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Open Access8 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)Impact (FWCI 0.07)OA: greenTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (16)

Jonathan R. Hart ORCID,BanuPriya Sridharan,Scott J. Novick ORCID,Lewis D. Turner ORCID,Bin Zhou ORCID

Live enrichment

PubMed:34130216 PMC:PMC8279689 OpenAlex:https://openalex.org/W3169713925

National Cancer Institute

Grant: R35 CA197582

National Cancer Institute

Grant: R50 CA243899

Scripps Research Institute

Skaggs Institute for Chemical Biology, Scripps Research Institute

National Institutes of Health

FWCI

0.07

Citation Percentile

0.4%

Citation Trend

2022

2025

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8279689

publisherhttps://api.elsevier.com/content/article/PII:S0968089621002546?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0968089621002546?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bmc.2021.116246

Fields of Study

Protein Degradation and InhibitorsClick Chemistry and ApplicationsInsect Resistance and GeneticsBinding SitesDose-Response Relationship, DrugDrug DevelopmentFluorescent DyesHigh-Throughput Screening AssaysHumansMolecular StructureProto-Oncogene Proteins c-mycStructure-Activity Relationship

MeSH Terms

Drug DevelopmentBinding SitesDose-Response Relationship, DrugFluorescent DyesHumansStructure-Activity RelationshipMolecular StructureProto-Oncogene Proteins c-mycHigh-Throughput Screening Assays

Keywords

ChemistryDrug discoveryHigh-throughput screeningSmall moleculeMutantFluorescenceChemical libraryDocking (animal)Active siteBinding siteBiochemistryCombinatorial chemistryBiophysicsEnzymeGeneBiologyMYCDockingOncoproteinHydrogen-deuterium Exchange Mass SpectrometryFluorescence Competition Assay