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Synthesis of sp3-rich chiral bicyclo[3.3.1]nonanes for chemical space expansion and study of biological activities

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2021.116561Source: DataRank Database

Synthesis of sp3-rich chiral bicyclo[3.3.1]nonanes for chemical space expansion and study of biological activities is a research paper published in Bioorganic & Medicinal Chemistry (2021). On theSindex it has a DataRank of 0. It has been cited 5 times.

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0DataRank · unranked

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5 citations

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Cite:

Linked data & code

CCDC 2121046: Experimental Crystal Structure Determination · Cambridge Crystallographic Data Centre

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 0.49)OA: closedTopics (55)Linked Datasets (1)DataCite Reuse (1)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (0/2)

Interoperable (2/2)

DataCite relations
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Reusable (0/3)

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Authors (3)

Peter Wipf ORCID,Hiroyuki Nakamura ORCID,Hiroki Ueda ORCID

Live enrichment

PubMed:34920311 OpenAlex:https://openalex.org/W4200324342

National Institutes of Health

Grant: 2P50GM067082

Japan Society for the Promotion of Science

Grant: 19J23200

JSPS

FWCI

0.49

Citation Percentile

0.6%

Citation Trend

2022

2023

2024

closedLicense: http://www.elsevier.com/open-access/userlicense/1.0/

publisherhttps://api.elsevier.com/content/article/PII:S0968089621005691?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0968089621005691?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bmc.2021.116561

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34920311

Fields of Study

Synthetic Organic Chemistry MethodsCancer, Hypoxia, and MetabolismMicrobial Natural Products and BiosynthesisAntineoplastic AgentsBridged Bicyclo CompoundsCell HypoxiaCell ProliferationCrystallography, X-RayDose-Response Relationship, DrugDrug Screening Assays, AntitumorHeLa CellsHumansHypoxia-Inducible Factor 1, alpha SubunitLigandsModels, MolecularMolecular StructureRNA, MessengerStructure-Activity RelationshipTumor Cells, Cultured

MeSH Terms

Antineoplastic AgentsBridged Bicyclo CompoundsDose-Response Relationship, DrugDrug Screening Assays, AntitumorHeLa CellsHumansLigandsModels, MolecularRNA, MessengerStructure-Activity RelationshipTumor Cells, CulturedMolecular StructureCell HypoxiaCrystallography, X-RayCell ProliferationHypoxia-Inducible Factor 1, alpha SubunitHela Cells

Keywords

ChemistryBicyclic moleculeStereochemistryAldehydeEnantioselective synthesisNonaneAldol reactionDiastereomerAldol condensationEnantiomerIntramolecular forceKetoneCatalysisOrganic chemistrystructural diversityhypoxia-inducible factorChemical SpaceSp(3)-richBicyclo[3.3.1]nonane

CCDC 2121046: Experimental Crystal Structure Determination

10.5517/ccdc.csd.cc2963vhCambridge Crystallographic Data Centre

Synthesis of sp3-rich chiral bicyclo[3.3.1]nonanes for chemical space expansion and study of biological activities

FAIR Checklist

Authors (3)

Funding (3 grants)

Impact

Open Access

Topics

Linked Datasets (1)