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Discovery of agonist–antagonist pairs for the modulation of Ca [2]+ and voltage-gated K+ channels of large conductance that contain beta1 subunits

Bioorganic & Medicinal Chemistry(2022)10.1016/j.bmc.2022.116876Source: DataRank Database

Discovery of agonist–antagonist pairs for the modulation of Ca [2]+ and voltage-gated K+ channels of large conductance that contain beta1 subunits is a research paper published in Bioorganic & Medicinal Chemistry (2022). On theSindex it has a DataRank of 0. It has been cited 2 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access2 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 0.16)OA: greenTopics (40)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Christy L. Dyer ORCID,Dejian Ma ORCID,Wěi Li ORCID,Anna N. Bukiya ORCID,Abby L. Parrill ORCID

Live enrichment

PubMed:35716586 PMC:PMC10464842 OpenAlex:https://openalex.org/W4282578032

National Institutes of Health

Grant: 1S10 OD010678-01

National Heart, Lung, and Blood Institute

Grant: RO1 HL147315

NIAAA NIH HHS

Grant: R01 AA011560

NHLBI NIH HHS

Grant: R01 HL147315

NIAAA NIH HHS

Grant: R37 AA011560

NIH HHS

Grant: S10 OD010678

FWCI

0.16

Citation Percentile

0.4%

Citation Trend

2023

2025

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10464842/pdf/nihms-1923480.pdf

BRONZEhttps://www.sciencedirect.com/science/article/am/pii/S0968089622002681

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10464842/pdf/nihms-1923480.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0968089622002681?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0968089622002681?httpAccept=text/plain

Fields of Study

Ion channel regulation and functionNicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology ResearchMedicineChemistryAnimalsCalciumCricetinaeCricetulusLarge-Conductance Calcium-Activated Potassium Channel beta SubunitsLarge-Conductance Calcium-Activated Potassium ChannelsPatch-Clamp Techniques

MeSH Terms

AnimalsCalciumCricetulusCricetinaePatch-Clamp TechniquesLarge-Conductance Calcium-Activated Potassium ChannelsLarge-Conductance Calcium-Activated Potassium Channel beta Subunits

Keywords

ChemistryAgonistAntagonistPharmacophoreBK channelActivator (genetics)Calcium-activated potassium channelBiophysicsPotassium channelVoltage-gated ion channelConductanceIon channelStereochemistryReceptorBiochemistryMembrane potentialDrug designStructure-activity relationshipAutomated Patch-clampMaxik ChannelBeta1 Subunit

Sustainable Development Goals

SDG 0: Good health and well-being