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Design, synthesis, and biological evaluation of a novel series of 1,2,4-oxadiazole inhibitors of SLACK potassium channels: Identification of in vitro tool VU0935685

Bioorganic & Medicinal Chemistry(2023)10.1016/j.bmc.2023.117487Source: DataRank Database

Design, synthesis, and biological evaluation of a novel series of 1,2,4-oxadiazole inhibitors of SLACK potassium channels: Identification of in vitro tool VU0935685 is a research paper published in Bioorganic & Medicinal Chemistry (2023). On theSindex it has a DataRank of 0. It has been cited 15 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access15 citations

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Linked data & code

BindingDB Entry 50020826: Design, synthesis, and biological evaluation of a novel series of 1,2,4-oxadiazole inhibitors of SLACK potassium channels: Identification of in vitro tool VU0935685. · BindingDB

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 1.38)OA: greenTopics (36)Linked Datasets (1)DataCite Reuse (1)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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Authors (5)

Brittany D. Spitznagel ORCID,Yu Du ORCID,C. David Weaver ORCID,Kyle A. Emmitte ORCID,Alshaima’a M. Qunies ORCID

Live enrichment

PubMed:37812884 PMC:PMC10842602 OpenAlex:https://openalex.org/W4387223560

NINDS NIH HHS

Grant: R33 NS109521

NIH HHS

Grant: S10 OD021734

FWCI

1.38

Citation Percentile

0.8%

Citation Trend

2024

2025

2026

greenLicense: http://www.elsevier.com/open-access/userlicense/1.0/

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10842602/pdf/nihms-1936972.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0968089623003358?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0968089623003358?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10842602

Fields of Study

Ion channel regulation and functionNeuroscience and Neuropharmacology ResearchEpilepsy research and treatment

MeSH Terms

Potassium Channels, Sodium-ActivatedAnimalsCricetulusCricetinaeHumansNerve Tissue ProteinsOxadiazolesSeizuresThalliumPotassium ChannelsMiceHEK293 Cells

Keywords

ChemistrySodium channelPotassium channelhERGHEK 293 cellsIn vitroLead compoundPatch clampBiophysicsPharmacologyBiochemistryReceptorSodiumBiology1,2,4-oxadiazolesSlo2.2SlackKcnt1MmpsiEimfsK(na)1.1

Sustainable Development Goals

SDG 0: Good health and well-being

BindingDB Entry 50020826: Design, synthesis, and biological evaluation of a novel series of 1,2,4-oxadiazole inhibitors of SLACK potassium channels: Identification of in vitro tool VU0935685.

10.7270/q2d2234tBindingDB